SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway

X Gu, JM Orozco, RA Saxton, KJ Condon, GY Liu… - Science, 2017 - science.org
mTOR complex 1 (mTORC1) regulates cell growth and metabolism in response to multiple
environmental cues. Nutrients signal via the Rag guanosine triphosphatases (GTPases) to …

Precise control of microtubule disassembly in living cells

GY Liu, SC Chen, GH Lee, K Shaiv, PY Chen… - The EMBO …, 2022 - embopress.org
Microtubules tightly regulate various cellular activities. Our understanding of microtubules is
largely based on experiments using microtubule‐targeting agents, which, however, are …

mTOR at the nexus of nutrition, growth, ageing and disease

GY Liu, DM Sabatini - Nature reviews Molecular cell biology, 2020 - nature.com
The mTOR pathway integrates a diverse set of environmental cues, such as growth factor
signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half …

Author Correction: mTOR at the nexus of nutrition, growth, ageing and disease

GY Liu, DM Sabatini - Nature Reviews Molecular Cell Biology, 2020 - nature.com
When discussing other nutritional inputs into mTORC1 (under the subheading ‘Amino acids
and other nutrients’), an additional reference (Ref. 281) was included, to acknowledge the …

Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor

SV Bradley, EC Holland, GY Liu, D Thomas, TS Hyun… - Cancer research, 2007 - AACR
Huntingtin interacting protein 1 (HIP1) is a multidomain oncoprotein whose expression
correlates with increased epidermal growth factor receptor (EGFR) levels in certain tumors. For …

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

GY Liu, P Jouandin, RE Bahng, N Perrimon… - Nature …, 2024 - nature.com
Animals sense and respond to nutrient availability in their environments, a task coordinated
in part by the mTOR complex 1 (mTORC1) pathway. mTORC1 regulates growth in response …

[HTML][HTML] Huntingtin-interacting protein 1: a Merkel cell carcinoma marker that interacts with c-Kit

HM Ames, CK Bichakjian, GY Liu… - Journal of investigative …, 2011 - Elsevier
Merkel cell carcinoma (MCC) is a neoplasm thought to originate from the neuroendocrine
Merkel cells of the skin. Although the prevalence of MCC has been increasing, treatments for …

Experience with 109 cases of transvaginal hydrolaparoscopy

ML Moore, M Cohen, GY Liu - The Journal of the American Association of …, 2003 - Elsevier
We conducted a prospective review of our experience with 109 transvaginal hydrolaparoscopies
(THLs) performed in 97 women. The THL was considered complete in 101 procedures (…

Detection of SARS CoV-2 contamination in the operating room and birthing room setting: risks to attending health care workers

…, AJM Yee, LH Gagnon, R Jenkinson, GY Liu - MedRxiv, 2021 - medrxiv.org
Background The exposure risks to front-line health care workers who are in close proximity
for prolonged periods of time, caring for COVID-19 patients undergoing surgery or obstetrical …

Surgical Outcomes between Routes of Hysterectomy in Patients with a Previous Cesarean Section

J Kroft, C McCaffrey, E Kim, C Jolliffe, GY Liu… - Journal of Minimally …, 2023 - Elsevier
… Author links open overlay panel Jamie Kroft MD, MSc a , Carmen McCaffrey MD, MSc a ,
Eliane Kim MPH b , Courtney Jolliffe MD a , Grace Y. Liu MD, MSc a , Refik Saskin MSc b , Jodi …