[HTML][HTML] Trial of minocycline in a clinically isolated syndrome of multiple sclerosis
…, P Duquette, M Eliasziw, G Cerchiaro… - … England Journal of …, 2017 - Mass Medical Soc
Background On the basis of encouraging preliminary results, we conducted a randomized,
controlled trial to determine whether minocycline reduces the risk of conversion from a first …
controlled trial to determine whether minocycline reduces the risk of conversion from a first …
A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation
M La, TV Cao, G Cerchiaro, K Chilton… - The American journal of …, 2003 - Elsevier
Galectin-1 (Gal-1), the prototype of a family of β-galactoside-binding proteins, has been
shown to attenuate experimental acute and chronic inflammation. In view of the fact that …
shown to attenuate experimental acute and chronic inflammation. In view of the fact that …
Assessing the efficacy and safety of hydroxychloroquine as outpatient treatment of COVID-19: a randomized controlled trial
I Schwartz, ME Boesen, G Cerchiaro… - … Open Access Journal, 2021 - cmajopen.ca
Background: Identification of therapies to prevent severe COVID-19 remains a priority. We
sought to determine whether hydroxychloroquine treatment for outpatients with SARS-CoV-2 …
sought to determine whether hydroxychloroquine treatment for outpatients with SARS-CoV-2 …
Hydroxychloroquine for primary progressive multiple sclerosis
…, J Kim, M Levesque‐Roy, G Cerchiaro… - Annals of …, 2021 - Wiley Online Library
Objective Primary progressive multiple sclerosis (PPMS) does not respond well to
immunomodulatory or immunosuppressive treatment. Chronic activation of microglia has been …
immunomodulatory or immunosuppressive treatment. Chronic activation of microglia has been …
Repurposing domperidone in secondary progressive multiple sclerosis: a Simon 2-stage phase 2 futility trial
MW Koch, K Sage, S Kaur, J Kim, G Cerchiaro… - Neurology, 2021 - AAN Enterprises
Objective To assess whether treatment with the generic drug domperidone can reduce the
progression of disability in secondary progressive multiple sclerosis (SPMS), we conducted a …
progression of disability in secondary progressive multiple sclerosis (SPMS), we conducted a …
Inducible nitric oxide synthase in rat neutrophils: role of insulin
GA Cerchiaro, C Scavone, S Texeira… - Biochemical …, 2001 - Elsevier
Defective leukocyte-endothelial interactions are observed in experimental diabetes mellitus.
Endogenous substances, including nitric oxide (NO), have anti-inflammatory effects within …
Endogenous substances, including nitric oxide (NO), have anti-inflammatory effects within …
Minocycline treatment in clinically isolated syndrome and serum NfL, GFAP, and metalloproteinase levels
…, J Greenfield, G Cerchiaro… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: In the trial of Minocycline in Clinically Isolated Syndrome (MinoCIS), minocycline
significantly reduced the risk of conversion to clinically definite multiple sclerosis (CDMS). …
significantly reduced the risk of conversion to clinically definite multiple sclerosis (CDMS). …
Feasibility study to assess lesion repair in relapsing-remitting multiple sclerosis: A Randomized Controlled Pilot Clinical trial of domperidone add-on treatment
…, WQ Liu, Z Hosseinpour, GB Pike, G Cerchiaro… - Multiple Sclerosis and …, 2024 - Elsevier
Background : Identification of therapies to promote repair in multiple sclerosis is challenged
by the lack of an accepted trial model and associated outcome measures. The goal of this …
by the lack of an accepted trial model and associated outcome measures. The goal of this …
Multimodal peripheral fluid biomarker analysis in clinically isolated syndrome and early multiple sclerosis
…, C Silva, LM Metz, G Cerchiaro… - Multiple Sclerosis and …, 2021 - Elsevier
Background Increasing evidence suggests that various inflammatory, immunological and
metabolic pathways are altered in the clinically isolated syndrome (CIS) of multiple sclerosis (…
metabolic pathways are altered in the clinically isolated syndrome (CIS) of multiple sclerosis (…
Interação leucócito-endotélio no diabetes mellitus: participação do óxido nítrico
GA Cerchiaro, P Sannomiya - 1999 - repositorio.usp.br
Defeitos na interação leucócito-endotélio são observados no diabetes mellitus.
Substâncias endógenas, incluindo o óxido nítricos exercem efeito anti inflamatório sobre a …
Substâncias endógenas, incluindo o óxido nítricos exercem efeito anti inflamatório sobre a …