Background: Antipsychotic drugs are widely used to manage behavioral and psychological
symptoms in dementia despite concerns about their safety. Objective: To examine the …

Background Cholinesterase inhibitors are commonly prescribed to treat dementia, but their
adverse effect profile has received little attention. These drugs can provoke symptomatic …

Purpose Most women diagnosed with breast cancer are younger than 65 years of age.
Population-based studies on cancer therapy–related cardiotoxicity have focused on older women…

Background Unplanned hospital readmissions are common, expensive and often preventable.
Strategies designed to reduce readmissions should target patients at high risk. The …

Importance Antibiotics are frequently and often inappropriately prescribed to patients in
nursing homes. These antibiotics pose direct risks to recipients and indirect risks to others …

RESEARCH Page 1 RESEARCH Levothyroxine dose and risk of fractures in older adults:
nested case-control study Marci R Turner, medical resident,1 Ximena Camacho, analyst,2 …

Context Both benign prostatic hyperplasia (BPH) and cataract formation are common in older
men. The α-adrenergic receptor blocker tamsulosin is frequently prescribed to treat BPH, …

Importance Given that most common bacterial infections can be treated with antibiotic courses
of 7 or fewer days, reducing standard antibiotic treatment durations may be an avenue to …

We evaluated risk of adverse respiratory outcomes associated with incident opioid use
among older adults with chronic obstructive pulmonary diseases (COPD). This was a …

Objectives Evaluation and optimization of antibiotic use (antibiotic stewardship) is being
increasingly promoted as a means to reduce antibiotic resistance, adverse events, treatment …