Cisplatin is a widely used and effective chemotherapeutic agent, although its use is restricted
by the high incidence of irreversible ototoxicity associated with it 1 . In children, cisplatin …

Background: Inappropriate prescribing increases patient illness and death owing to adverse
drug events. The inclusion of genetic information into primary care medication practices is …

We describe a method for pooling and sequencing DNA from a large number of individual
samples while preserving information regarding sample identity. DNA from 576 individuals …

Background Human respiratory syncytial virus (HRSV) is one of the major etiologic agents of
respiratory tract infections among children worldwide. Methodology/Principal Findings Here …

Objective A simple, non-invasive sample collection method is key for the integration of
pharmacogenetics into clinical practice. The aim of this study was to gain samples for …

Background The study of genetic variation as a factor influencing drug safety, efficacy, and
effectiveness has brought about significant breakthroughs in understanding the clinical …

Pharmacogenetic Pharmacogenetics clinical algorithms Clinical Algorithms represented by
logistic steps in the decision-making process are designed to shift pharmacogenetics from …

The identification of germline variants that predispose to cancer is important to further our
understanding of tumorigenesis, guide patient management, prevent disease in unaffected …

… Colin JD Ross, Hagit Katzov-Eckert, Marie-Pierre Dubé, Beth Brooks, S Rod Rassekh,
Amina Barhdadi, Yassamin Feroz-Zada, Henk Visscher, Andrew MK Brown, Michael J …

Dear Editor Maruf et al. 1 have comprehensively reviewed pharmacogenetic testing options
relevant to psychiatry that are available in Canada. In the discussion, the authors point out …