Tiotropium in combination with placebo, salmeterol, or fluticasone–salmeterol for treatment of chronic obstructive pulmonary disease: a randomized trial
…, G Ford, D Bleskie, S Doucette, I Mayers… - Annals of internal …, 2007 - acpjournals.org
Background: Treatment of moderate or severe chronic obstructive pulmonary disease (COPD)
with combinations of inhaled corticosteroids, long-acting β-agonists, and long-acting …
with combinations of inhaled corticosteroids, long-acting β-agonists, and long-acting …
Long-term compliance rates to continuous positive airway pressure in obstructive sleep apnea: a population-based study
DD Sin, I Mayers, GCW Man, L Pawluk - Chest, 2002 - Elsevier
Study objectives To determine long-term compliance rates to continuous positive airway
pressure (CPAP) therapy in patients with obstructive sleep apnea enrolled in a comprehensive …
pressure (CPAP) therapy in patients with obstructive sleep apnea enrolled in a comprehensive …
Reevaluation of diagnosis in adults with physician-diagnosed asthma
Importance Although asthma is a chronic disease, the expected rate of spontaneous
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …
remissions of adult asthma and the stability of diagnosis are unknown. Objective To determine …
Managing dyspnea in patients with advanced chronic obstructive pulmonary disease: a Canadian Thoracic Society clinical practice guideline
…, F Maltais, RA Mularski, AJ Cave, I Mayers… - Canadian respiratory …, 2011 - hindawi.com
Dyspnea is a cardinal symptom of chronic obstructive pulmonary disease (COPD), and its
severity and magnitude increases as the disease progresses, leading to significant disability …
severity and magnitude increases as the disease progresses, leading to significant disability …
Predictors of survival following in-hospital adult cardiopulmonary resuscitation
PG Brindley, DM Markland, I Mayers, DJ Kutsogiannis - Cmaj, 2002 - Can Med Assoc
Background: This study was undertaken to provide up-to-date survival data for Canadian
adult in-patients following attempted resuscitation from cardiac or respiratory arrest. We hope …
adult in-patients following attempted resuscitation from cardiac or respiratory arrest. We hope …
Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis
…, J Fraiz, JE Stasek Jr, JA Russell, I Mayers… - Critical care …, 2001 - journals.lww.com
… MD; Mayers, Irvin MD; Rosenfeld, Brian A. MD; Morris, Peter E. MD; Yan, S. … Mayers,
MD, University of Alberta, Edmonton, Alberta, Canada (11); B. Rosenfeld, MD, Johns …
MD, University of Alberta, Edmonton, Alberta, Canada (11); B. Rosenfeld, MD, Johns …
Distribution of nitric oxide synthase in normal and cirrhotic human liver
…, N Kneteman, I Mayers… - Proceedings of the …, 2002 - National Acad Sciences
Chronic liver disorders represent a serious health problem, considering that 300 million
people worldwide are hepatitis B virus carriers, and 8,000–10,000 patients per year, in the US …
people worldwide are hepatitis B virus carriers, and 8,000–10,000 patients per year, in the US …
Matrix metalloproteinase 2 in tumor cell-induced platelet aggregation: regulation by nitric oxide
…, G Sawicki, M Duszyk, J Sawicka, C Miranda, I Mayers… - Cancer research, 2001 - AACR
A correlation exists between the ability of tumor cells to aggregate platelets and their
tendency to metastasize. Tumor cell-induced platelet aggregation (TCIPA) facilitates the …
tendency to metastasize. Tumor cell-induced platelet aggregation (TCIPA) facilitates the …
Efficacy and safety of multiple doses of QGE031 (ligelizumab) versus omalizumab and placebo in inhibiting allergen-induced early asthmatic responses
Background Omalizumab is an established anti-IgE therapy for the treatment of allergic
diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE …
diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE …
Targeting membrane-expressed IgE B cell receptor with an antibody to the M1 prime epitope reduces IgE production
…, B Dahlén, Y Wang, R Maciuca, I Mayers… - Science Translational …, 2014 - science.org
Elevated serum levels of both total and allergen-specific immunoglobulin E (IgE) correlate
with atopic diseases such as allergic rhinitis and allergic asthma. Neutralization of IgE by anti-…
with atopic diseases such as allergic rhinitis and allergic asthma. Neutralization of IgE by anti-…