… The current iteration of this article differs from that of Douketis et al 6 in the Antithrombotic
and Thrombolytic Therapy: American College of Chest Physicians Evidence-Based Clinical …

Obesity is now reaching epidemic proportions in both developed and developing countries
and is affecting not only adults but also children and adolescents. Over the last 20 years, …

Background Warfarin is a highly efficacious oral anticoagulant, but its use is limited by a well-founded
fear of bleeding. Drug and food interactions are frequently cited as causes of …

Background It is uncertain whether bridging anticoagulation is necessary for patients with
atrial fibrillation who need an interruption in warfarin treatment for an elective operation or …

… JD Douketis—no relevant conflicts for present work. Consulting fees or honoraria from …
James D. Douketis contributed to the concept, analysis/interpretation of data, critical writing, …

Background Patients who have a first episode of venous thromboembolism in the absence
of known risk factors for thrombosis (idiopathic thrombosis) are often treated with …

This article discusses the perioperative management of antithrombotic therapy and is part of
the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th …

Background: Clinicians should consider the clinical impact of anticoagulant-related
bleeding when deciding on the duration of anticoagulant therapy in patients with venous …

Background Many patients with the antiphospholipid antibody syndrome and recurrent
thrombosis receive doses of warfarin adjusted to achieve an international normalized ratio (INR) …

Context.—The most serious complication of deep vein thrombosis (DVT) or nonfatal pulmonary
embolism (PE) is fatal PE. However, reliable estimates as to the risk of fatal PE in patients …