ContextThe prevalence of overweight and obesity in children and adolescents is increasing
rapidly. In this population, behavioral therapy alone has had limited success in providing …

OBJECTIVE. We designed and tested a novel health promotion program for elementary schools
that was based on peer teaching from older to younger schoolchildren (“Healthy Buddies…

To determine whether peptide YY (PYY), ghrelin, glucose-dependent insulinotropic
polypeptide (GIP), and satiety responses to food intake are impaired in anorexia or obesity, we …

Congenital hypogonadotropic hypogonadism (CHH) and its anosmia-associated form (Kallmann
syndrome [KS]) are genetically heterogeneous. Among the >15 genes implicated in …

Context: Increased physical activity is an integral part of weight loss programs in adolescents.
We hypothesized that exercise could affect appetite-regulating hormones and the …

The voluem of the thyroid gland was determined by ultrasonography in 256 euthyroid subjects
aged 0–20 years in Brussels, an area with borderline iodine intake (median urinary iodine…

In rats, the respective contribution of the thyroid and peripheral tissues to the pool of T3
remains unclear. Most, if not all, of the circulating T3 produced by extrathyroidal sources is …

T4 is bound to transthyretin (TTR; 75%) and albumin (Alb; 25%) in rat serum and only to TTR
in cerebrospinal fluid (CSF). In addition to the liver, TTR is synthesized in large amounts in …

Ghrelin is an orexigenic peptide secreted mainly by the stomach in adult rats. Ghrelin
concentrations increase with fasting and decrease after food intake. Ghrelin is also present in the …

Ghrelin has orexigenic effects. It is present in umbilical cord plasma in full-term neonates,
raising the prospect that ghrelin plays a role in fetal and neonatal energy balance. We …