Photodynamic therapy with Pd‐bacteriopheophorbide (TOOKAD): Successful in vivo treatment of human prostatic small cell carcinoma xenografts

NV Koudinova, JH Pinthus, A Brandis… - … journal of cancer, 2003 - Wiley Online Library
Small cell carcinoma of the prostate (SCCP), although relatively rare, is the most aggressive
variant of prostate cancer, currently with no successful treatment. It was therefore tempting to …

Population based survival data on urachal tumors

JH Pinthus, R Haddad, J Trachtenberg… - The Journal of …, 2006 - auajournals.org
Purpose : Urachal carcinoma accounts for less than 1% of all bladder cancers. Limited data
exist on disease related outcomes originating from case reports and select referral centers. …

Prostate cancers scored as Gleason 6 on prostate biopsy are frequently Gleason 7 tumors at radical prostatectomy: implication on outcome

JH Pinthus, M Witkos, NE Fleshner, J Sweet… - The Journal of …, 2006 - auajournals.org
Purpose : Differentiation between Gleason score 6 and 7 in prostate biopsy is important for
treatment decision making. Nevertheless, under grading errors compared with the actual …

Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft

A Bar-Shira, JH Pinthus, U Rozovsky, M Goldstein… - Cancer research, 2002 - AACR
We analyzed a prostate cancer xenograft derived from a locally advanced tumor using combined
cytogenetic, array-based comparative genomic hybridization and expression analyses. …

Cardiovascular morbidity in a randomized trial comparing GnRH agonist and GnRH antagonist among patients with advanced prostate cancer and preexisting …

…, E Rosenbaum, JH Pinthus - The Journal of …, 2019 - auajournals.org
Purpose: Androgen deprivation therapy may increase the risk of cardiovascular disease.
Limited data suggest that GnRH (gonadotropin-releasing hormone) antagonist may be …

Testosterone and prostate cancer: revisiting old paradigms

H Isbarn, JH Pinthus, LS Marks, F Montorsi, A Morales… - European urology, 2009 - Elsevier
CONTEXT: Androgens are vital for growth and maintenance of the prostate; however, the
notion that pathologic prostate growth, benign or malignant, can be stimulated by androgens is …

Androgen induces adaptation to oxidative stress in prostate cancer: implications for treatment with radiation therapy

JH Pinthus, I Bryskin, J Trachtenberg, JP Luz, G Singh… - Neoplasia, 2007 - Elsevier
Radiation therapy is a standard treatment for prostate cancer (PC). The postulated
mechanism of action for radiation therapy is the generation of reactive oxygen species (ROS). …

[HTML][HTML] The potential role of follicle-stimulating hormone in the cardiovascular, metabolic, skeletal, and cognitive effects associated with androgen deprivation therapy

ED Crawford, AV Schally, JH Pinthus, NL Block… - … Oncology: Seminars and …, 2017 - Elsevier
Purpose To explore how follicle-stimulating hormone (FSH) may contribute to cardiovascular,
metabolic, skeletal, and cognitive events in men treated for prostate cancer, with various …

Photodynamic therapy for urological malignancies: past to current approaches

JH Pinthus, A Bogaards, R Weersink, BC Wilson… - The Journal of …, 2006 - Elsevier
PURPOSE: Modern PDT for urological tumors is a potentially selective approach in which in
situ photosensitization by a nontoxic drug, locally activated by light, generates cytotoxic …

Lower plasma adiponectin levels are associated with larger tumor size and metastasis in clear-cell carcinoma of the kidney

JH Pinthus, N Kleinmann, B Tisdale, S Chatterjee… - European urology, 2008 - Elsevier
OBJECTIVES: To examine a possible relationship between plasma adiponectin levels and
renal cell carcinoma (RCC). Adiponectin, a cytokine secreted by adipocytes, is a potent …