Biomarkers in acute respiratory distress syndrome
A Binnie, JLY Tsang… - Current opinion in critical …, 2014 - journals.lww.com
This article summarizes the current status of ARDS biomarker research and provides a
framework for future investigation.
framework for future investigation.
Epigenetics of sepsis
Objectives: Recent evidence from the fields of microbiology and immunology, as well as a
small number of human sepsis studies, suggest that epigenetic regulation may play a central …
small number of human sepsis studies, suggest that epigenetic regulation may play a central …
Effect of awake prone positioning on endotracheal intubation in patients with COVID-19 and acute respiratory failure: a randomized clinical trial
…, J Chalabi, AA Rahmatullah, E Duan, JLY Tsang… - Jama, 2022 - jamanetwork.com
Importance The efficacy and safety of prone positioning is unclear in nonintubated patients
with acute hypoxemia and COVID-19. Objective To evaluate the efficacy and adverse events …
with acute hypoxemia and COVID-19. Objective To evaluate the efficacy and adverse events …
Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study
…, A Swanson, H Tessier-Grenier, JLY Tsang… - … Open Access Journal, 2021 - cmajopen.ca
Background: Clinical data on patients admitted to hospital with coronavirus disease 2019 (COVID-19)
provide clinicians and public health officials with information to guide practice and …
provide clinicians and public health officials with information to guide practice and …
[HTML][HTML] Psychosocial distress amongst Canadian intensive care unit healthcare workers during the acceleration phase of the COVID-19 pandemic
A Binnie, K Moura, C Moura, F D'Aragon, JLY Tsang - PLoS One, 2021 - journals.plos.org
Intensive care unit healthcare workers (ICU HCW) are at risk of mental health issues during
emerging disease outbreaks. A study of ICU HCW from France revealed symptoms of anxiety …
emerging disease outbreaks. A study of ICU HCW from France revealed symptoms of anxiety …
[HTML][HTML] External validation of the 4C mortality score among COVID-19 patients admitted to hospital in Ontario, Canada: a retrospective study
…, J Kapralik, R Patel, E Feng, L Dawson, JLY Tsang… - Scientific reports, 2021 - nature.com
Risk prediction scores are important tools to support clinical decision-making for patients
with coronavirus disease (COVID-19). The objective of this paper was to validate the 4C …
with coronavirus disease (COVID-19). The objective of this paper was to validate the 4C …
DJ-1/PARK7 impairs bacterial clearance in sepsis
…, ER Speck, AE Fox-Robichaud, JLY Tsang… - American Journal of …, 2017 - atsjournals.org
Rationale: Effective and rapid bacterial clearance is a fundamental determinant of outcomes
in sepsis. DJ-1 is a well-established reactive oxygen species (ROS) scavenger. Objectives: …
in sepsis. DJ-1 is a well-established reactive oxygen species (ROS) scavenger. Objectives: …
Small-volume blood collection tubes to reduce transfusions in intensive care: the STRATUS randomized clinical trial
…, F Marquis, JF Naud, J Shahin, J Shea, JLY Tsang… - JAMA, 2023 - jamanetwork.com
Importance Blood collection for laboratory testing in intensive care unit (ICU) patients is a
modifiable contributor to anemia and red blood cell (RBC) transfusion. Most blood withdrawn is …
modifiable contributor to anemia and red blood cell (RBC) transfusion. Most blood withdrawn is …
Epigenetic profiling in severe sepsis: a pilot study of DNA methylation profiles in critical illness
…, A Fox-Robichaud, PC Liaw, JLY Tsang… - Critical Care …, 2020 - journals.lww.com
Objectives: Epigenetic alterations are an important regulator of gene expression in health
and disease; however, epigenetic data in sepsis are lacking. To demonstrate proof of concept …
and disease; however, epigenetic data in sepsis are lacking. To demonstrate proof of concept …
Qualitative descriptive study to explore nurses' perceptions and experience on pain, agitation and delirium management in a community intensive care unit
JLY Tsang, K Ross, F Miller, R Maximous, P Yung… - BMJ open, 2019 - bmjopen.bmj.com
Objectives The purpose of this study was to explore the experiences, beliefs and perceptions
of intensive care unit (ICU) nurses on the management of pain, agitation and delirium (PAD…
of intensive care unit (ICU) nurses on the management of pain, agitation and delirium (PAD…