The SWI/SNF (mating type SWItch/Sucrose NonFermentable) chromatin remodeling
complexes interact with histones and transcription factors to modulate chromatin structure and …

Clear cell ovarian carcinoma (CCOC) and clear cell renal cell carcinoma (ccRCC) both
feature clear cytoplasm, owing to the accumulation of cytoplasmic glycogen. Genomic studies …

Aims Differentiated vulvar intraepithelial neoplasia (dVIN), the precursor lesion to human
papillomavirus‐independent vulvar squamous cell carcinoma (VSCC), can be difficult to …

Clear cell ovarian carcinoma (CCOC) is the second most common subtype of epithelial
ovarian carcinoma. Late‐stage CCOC is not responsive to gold‐standard chemotherapy and …

Purpose: Many rare ovarian cancer subtypes, such as small-cell carcinoma of the ovary,
hypercalcemic type (SCCOHT), have poor prognosis due to their aggressive nature and …

Clinical investigators within the Canadian and international communities were shocked when
the Canadian Institutes of Health Research (CIHR) announced that their funding for the MD…

Mesonephric carcinoma is a rare gynecologic neoplasm commonly mistaken for clear cell
carcinoma, because of their overlapping morphologic features. Both tumors are negative for …

Background: Combined MD/PhD programs provide a structured path for physician-scientist
training, but assessment of their success within Canada is limited by a lack of quantitative …

Conventional cytotoxic therapies for synovial sarcoma provide limited benefit. Drugs specifically
targeting the product of its driver translocation are currently unavailable, in part because …

The diagnosis of clear cell (CC) carcinoma of the endometrium can be challenging, especially
when endometrioid (EC) and serous (SC) endometrial cancers exhibit nonspecific clear …