Objective To assess if early clinical and electroencephalography (EEG) features predict
later seizure development in infants with hypoxic‐ischemic encephalopathy (HIE). Methods …

In addition to cognitive decline, individuals affected by Alzheimer’s disease (AD) can experience
important neuropsychiatric symptoms including sleep disturbances. We characterized …

Background and Purpose: Many patients with ischemic stroke present with multiple comorbidities
that threaten survival and recovery. This study sought to determine the risks of adverse …

Tumor necrosis factor-alpha (TNFα) regulates neuronal excitability. We investigated whether
alterations in the level of TNFα occur at a time point that precedes the reported seizure-…

Background The incidence of ischemic stroke has increased among adults aged 18 to 64
years, yet little is known about relationships between specific risk factors and outcomes. This …

Noradrenaline (NE) plays an integral role in shaping behavioral outcomes including anxiety/depression,
fear, learning and memory, attention and shifting behavior, sleep-wake state, …

Background Despite extensive research on neonatal hypoxic-ischaemic encephalopathy,
detailed information about electrographic seizures during active cooling and rewarming of …

The relationship between heightened neuroinflammation and cognitive decline in the
normally aged brain is still debatable, as most data are derived from insult-related models. …

Alterations in cytokine expression as well as deficits in synaptic activity are two features
observed in early, prodromal stages of Alzheimer’s disease (AD). The cytokines TNF-α and IL-1β …

Background Low serum osteocalcin is a risk factor for type 2 diabetes mellitus (T2DM), and
osteocalcin release from bone is associated with an acute stress response in mice. Both …