Background Efavirenz (EFV) is used as part of a highly active antiretroviral therapy (ART)
regimen (HAART) against HIV-1 infection 1, 2. It is important to achieve the correct dosage of …

Chromatin structure is dynamically modulated by various chromatin modifications, such as
histone/DNA methylation and demethylation. We have reviewed histone methyltransferases …

Background: Canadian guidelines recommend against population-based screening for
prostate cancer because of the risk of over-diagnosis and overtreatment. We sought to assess …

The imprints of domestication and breed development on the genomes of livestock likely differ
from those of companion animals. A deep draft sequence assembly of shotgun reads from …

To understand the biology and evolution of ruminants, the cattle genome was sequenced to
about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a …

Methods A simple random sample of 10 000 abdominal ultrasound (US) and computed
tomography (CT) reports was drawn from our hospital’s data warehouse. Reports were manually …

Background: Canadian guidelines recommend against population-based screening for
prostate cancer because of the risk of overdiagnosis and overtreatment. We sought to assess …

This paper proposes the use of microprocessor performance counters for online measurement
of complete system power consumption. The approach takes advantage of the "trickle-…

Semaglutide, a glucagon-like peptide 1 (GLP-1) analog, induces weight loss, lowers glucose
levels, and reduces cardiovascular risk in patients with diabetes. Mechanistic preclinical …

Perfluoroalkyl acids such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA)
have applications in numerous industrial and consumer products. Although the …