Despite autonomic dysfunction after spinal cord injury (SCI) being the major cause of death
and a top health priority, the clinical management options for these conditions are limited to …

Differential expression analysis in single-cell transcriptomics enables the dissection of cell-type-specific
responses to perturbations such as disease, trauma, or experimental …

After spinal cord injury, tissue distal to the lesion contains undamaged cells that could support
or augment recovery. Targeting these cells requires a clearer understanding of their injury …

Advances in single-cell genomics now enable large-scale comparisons of cell states across
two or more experimental conditions. Numerous statistical tools are available to identify …

Spinal cord injury (SCI) induces haemodynamic instability that threatens survival 1 , 2 – 3 ,
impairs neurological recovery 4 , 5 , increases the risk of cardiovascular disease 6 , 7 , and …

A spinal cord injury disrupts communication between the brain and the circuits in the spinal
cord that regulate neurological functions. The consequences are permanent paralysis, loss …

Axon regeneration can be induced across anatomically complete spinal cord injury (SCI),
but robust functional restoration has been elusive. Whether restoring neurological functions …

A spinal cord injury interrupts pathways from the brain and brainstem that project to the
lumbar spinal cord, leading to paralysis. Here we show that spatiotemporal epidural electrical …

People with late-stage Parkinson’s disease (PD) often suffer from debilitating locomotor
deficits that are resistant to currently available therapies. To alleviate these deficits, we …

Objective: To determine whether spinal cord perfusion pressure (SCPP) as measured with a
lumbar intrathecal catheter is a more predictive measure of neurologic outcome than the …