Promising efficacy results of chimeric antigen receptor (CAR) T-cell therapy have been tempered
by safety considerations. Our objective was to comprehensively summarize the efficacy …

Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) can reduce inflammation,
promote healing, and improve organ function, thereby providing a potential “cell-free” therapy…

Preclinical and clinical evidence suggests that mesenchymal stem cells (MSCs) may be
beneficial in treating both acute myocardial infarction (AMI) and ischemic heart failure (IHF). …

Tranexamic acid (TXA) is an effective hemostatic agent used for the reduction of blood loss
and transfusion. However, the safety profile of TXA remains in question due to a potential …

Plain English summary With the growing movement to engage patients in research,
questions are being asked about who is engaging patients and how they are being engaged. …

Preclinical studies suggest mesenchymal stromal cell extracellular vesicles (MSC‐EVs)
reduce inflammation and improve organ function in lung diseases; however, an objective …

There may be the potential to improve stroke recovery with mesenchymal stem cells (MSCs);
however, questions about the efficacy and safety of this treatment remain. To address these …

Background ‘Patient engagement' involves meaningful collaboration between researchers
and ‘patient partners' to co-create research. It helps ensure that research being conducted is …

Background The American College of Surgeons’ National Surgical Quality Improvement
Program (NSQIP) is the first nationally validated, risk-adjusted, outcomes-based program to …

We conducted a systematic review and meta-analysis of randomized control trials to formally
assess the safety and efficacy of autologous whole cell vaccines as immunotherapies for …