B-cell depletion may impair vaccine responses and increase infection risk in patients with
immune thrombocytopenia (ITP). We investigated the effects of rituximab on antibody and …

This phase 1 study evaluated the safety, tolerability, pharmacokinetics, and antitumor activity
of obinutuzumab (GA101), a glycoengineered type II anti-CD20 monoclonal antibody …

The benefit of adding rituximab to standard treatment in nonsplenectomized patients with
primary immune thrombocytopenia (ITP) is uncertain. We performed a pilot randomized trial to …

Desmopressin (DDAVP) is commonly used in the treatment of patients with type 1 von
Willebrand disease (VWD) and mild hemophilia A. A patient's responsiveness to DDAVP based …

Advanced-stage mantle cell lymphoma (MCL) is a disease for which no curative treatment
strategy exists. Results with standard combination chemotherapy, with or without an …

Background. Secondary erythrocytosis is classically defined by an increase in erythropoietin
(EPO) production. Despite increased levels of EPO often seen in secondary erythrocytosis, …

Although patients with Hodgkin lymphoma treated with adriamycin, bleomycin, vinblastine
and dacarbazine (ABVD) chemotherapy frequently develop neutropenia, febrile neutropenia …

OBJECTIVE: Critically ill neonates frequently require multiple small volume red blood cell (RBC)
transfusions. RBC units assigned to individual infants, used sequentially in small …

Background Mediastinal radiation can accelerate atherosclerosis in Hodgkin lymphoma
survivors (HLS), and early detection is optimal. Peripheral arterial tonometry (PAT), a non-…

Abstract 934 Background: GA101 (RO5072759) is the first humanized glycoengineered
type II anti-CD20 monoclonal antibody to enter clinical trials. Preclinical studies have shown …