Objective To update recommendations for antiretroviral therapy for adult human immunodeficiency
virus type 1 (HIV-1) infection, based on new information and drugs that are available. …

ObjectiveNew information warrants updated recommendations for the 4 central issues in
antiretroviral therapy: when to start, what drugs to start with, when to change, and what to …

Continuing expansion of the HIV/AIDS pandemic has been recognised as an exceptional
challenge to global health, international development, and world security. UNAIDS estimates …

Context The availability of new antiretroviral drugs and formulations, including drugs in new
classes, and recent data on treatment choices for antiretroviral-naive and -experienced …

Background The T-20 vs. Optimized Regimen Only Study 1 (TORO 1) was a randomized,
open-label, phase 3 study of enfuvirtide (T-20), a human immunodeficiency virus type 1 (HIV-1) …

Context Recent data regarding the consequences of untreated human immunodeficiency
virus (HIV) infection and the expansion of treatment choices for antiretroviral-naive and …

ContextGuidelines for antiretroviral therapy are important for clinicians worldwide given the
complexity of the field and the varied clinical situations in which these agents are used. The …

Context.—Clinical trials have established the efficacy of antiretroviral therapy with double-
and triple-drug regimens for individuals infected with the human immunodeficiency virus (HIV)…

Context.—Current guidelines recommend that individuals infected with the human
immunodeficiency virus type 1 (HIV-1) be treated using combinations of antiretroviral agents to …

ContextCurrent recommendations for initiation of antiretroviral therapy in patients infected
with human immunodeficiency virus type 1 (HIV) are based on CD4 T-lymphocyte cell counts …