… PJ Devereaux, Gordon Guyatt, Emil Schemitsch and Justin DeBeer contributed substantially
to the conception and design of the study and revised the article for important intellectual …

The role of mitochondrial dysfunction and oxidative stress has been extensively characterized
in the aetiology of sarcopenia (aging-associated loss of muscle mass) and muscle wasting …

Background Observational studies have suggested that accelerated surgery is associated
with improved outcomes in patients with a hip fracture. The HIP ATTACK trial assessed …

Retrospective review of 1216 primary total knee arthroplasties (TKAs) to evaluate incidence
and predictors of arthrofibrosis, defined as flexion less than 90 1 year post-TKA. Incidence of …

Importance Patients undergoing surgery for a hip fracture have a higher risk of mortality and
major complications compared with patients undergoing an elective total hip replacement (…

We analyzed the reproducibility and reliability of computer templating in primary uncemented
total hip arthroplasties as compared to standard onlay templating techniques with …

Background Standard therapy (ST) for postoperative pain after knee and hip replacement at
the Hamilton Health Sciences Henderson Hospital consists of epidural analgesia or patient-…

The role of nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) and Kelch-like ECH-associated
protein 1 (Keap1) redox signaling has not been characterized in human skeletal muscle …

Given institutional pressures to reduce hospital length of stay (LOS) we hypothesized that “failure
to cope” would be a significant factor for readmission following total joint arthroplasty (…

Objective: To determine the level of physical activity participants are able to perform at a
minimum of 1 year after primary total hip or knee replacement. Design: Cross-sectional survey. …