Hepatitis B virus (HBV) infection is an important public health problem in Canada. In keeping
with evolving evidence and understanding of HBV pathogenesis, the Canadian Association …

Background The COVID-19 pandemic has been associated with increased antimicrobial use
despite low rates of bacterial co-infection. Prospective audit and feedback is recommended …

Oseltamivir is the ethyl ester prodrug of the antiviral molecule, oseltamivir carboxylate, a
potent and selective inhibitor of influenza A and B neuraminidase (NA) (sialidase). It is highly …

Background & Aims HDV affects 4.5–13% of chronic hepatitis B (CHB) patients globally, yet
the prevalence of HDV infection in Canada is unknown. To investigate the prevalence, …

Background. BK virus-associated nephropathy is an important cause of renal dysfunction in
renal transplant recipients. Renal dysfunction after nonrenal solid organ transplantation (…

Background: Published Canadian epidemiologic data on hepatitis B virus (HBV) infection
include single-centre studies or are focused on Indigenous populations. We performed a study …

Spleen transplantation (SpTx) was performed in miniature swine across full major histocompatibility
complex barriers to study the tolerogenic effect of the spleen. This study describes …

Background The use of broad-spectrum antibiotics is widespread in patients with COVID-19
despite a low prevalence of bacterial co-infection, raising concerns for the accelerated …

International guidelines list hepatitis C virus (HCV) as a contraindication to lung transplant (LTx).
Since the development of these guidelines, the natural history of HCV after nonhepatic …

Liver transplantation for human immunodeficiency virus (HIV) positive patients with viral
hepatitis co-infection is increasingly offered in many North American and European liver …