Background A 9-month regimen of isoniazid can prevent active tuberculosis in persons with
latent tuberculosis infection. However, the regimen has been associated with poor …

Objective: There is a lack of consensus on how long circulation must cease for death to be
determined after cardiac arrest. The lack of scientific evidence concerning autoresuscitation …

Background The treatment of latent infection with Mycobacterium tuberculosis is important in
children because of their vulnerability to life-threatening forms of tuberculosis disease. The …

This 2023 Clinical Practice Guideline provides the biomedical definition of death based on
permanent cessation of brain function that applies to all persons, as well as …

Objectives: Create trustworthy, rigorous, national clinical practice guidelines for the practice
of pediatric donation after circulatory determination of death in Canada. Methods: We …

To identify reasons why hearts and lungs from consented adult organ donors are not
transplanted and identify changes in practice aimed at increasing their utilization rates. A greater …

Background: Tuberculosis predominantly affects socioeconomically disadvantaged
communities. The extent to which specific dietary and lifestyle factors contribute to tuberculosis …

… Karen Hornby BSCN,* Sam D. Shemie MD,* Jeanni Teitelbaum MD,† Christopher Doig
MD MSc‡ … Hornby et al.: VARIABILITY IN CANADIAN BRAIN DEATH GUIDELINES …

Background: Between November 2011 and November 2012, an Inuit village in Nunavik,
Quebec experienced a surge in the occurrence of active TB; contact investigations showed that …

Introduction Many transplant centers utilize a hard cutoff of 2 hours of warm ischemic time (WIT),
defined as the time from withdrawal of life‐sustaining measures to cold organ flush, to …