Objective To report trends in event and case fatality rates for acute myocardial infarction and
examine the relative contributions of changes in these rates to changes in total mortality …

Introduction British Columbia (BC), Canada declared a public health emergency in April
2016 for opioid overdose. Comprehensive data was needed to identify risk factors, inform …

Background British Columbia is the epicenter of the current fentanyl-related overdose crisis
in Canada. Our study characterizes prescribing histories of people who had an opioid-…

Background— The prevalence of the use of secondary prevention cardiovascular medications
is lower among women than men, but it is unclear if this is a result of lower treatment …

Purpose The aim of this study is to examine the relationship between domperidone (commonly
used off‐label for lactation stimulation), ventricular arrhythmia and all‐cause mortality …

Background— There are limited population-based national data on prognosis in survivors
of acute myocardial infarction (AMI), particularly on long-term survival and the risk of …

Aims/hypothesis Type 2 diabetes increases the risk of subsequent dementia. Our objective
was to determine whether a similar risk of subsequent dementia is associated with type 1 …

Purpose To describe trends, patterns, and determinants of prescription drug use during
pregnancy and postpartum. Methods This is a retrospective, population-based study of all …

Objectives: to measure sex differences in the risk of receiving potentially inappropriate
prescription drugs and to examine what are the factors that contribute to these differences. Design…

" Canadians spent almost $23-billion on prescription drugs at retail pharmacies in 2012/13–or
over $650 per capita. That is a lot of money. However, after adjusting for general inflation, …