Description: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease
with an estimated prevalence of 1 in 5000 that is characterized by the presence of vascular …

This is an update to the 2014 Canadian Hereditary Angioedema Guideline with an expanded
scope to include the management of hereditary angioedema (HAE) patients worldwide. It …

Hereditary angioedema (HAE) is a disease which is associated with random and often
unpredictable attacks of painful swelling typically affecting the extremities, bowel mucosa, genitals…

Background The aim of the Building on Existing Tools to Improve Chronic Disease Prevention
and Screening in Family Practice (BETTER) randomized controlled trial is to improve the …

Objective To develop and encourage the adoption of clinical practice guidelines (CPGs) for
smoking cessation in Canada by engaging stakeholders in the adaptation of existing high-…

Pyruvate kinase (PK) deficiency is the most common cause of chronic congenital non-spherocytic
haemolytic anaemia worldwide, with an estimated prevalence of one in 100 000 to one …

… , Hilary Longhurst18, Marc Riedl19, Bruce Zuraw19, Magdelena Berger20, Jean‑Nicolas
Boursiquot21, Henrik Boysen22, Anthony Castaldo23, Hugo Chapdelaine24, Lori Connors7 …

To be successful, healthcare improvement interventions must be aligned with the relevant
evidence; so the search, appraisal, and summary of evidence is a key element in CEP’s …

BACKGROUND (INTRODUCTION): Social marketing efforts in both domestic and
international settings have been successful at improving the lives and health status of targeted …

METHODS We conducted a qualitative study of focus groups (FGs) with physicians (guideline
developers, users, and a mixed group) involved in cardiovascular care to identify optimal …