User profiles for Kelly Monaghan

Kelly Monaghan

West Virginia University
Verified email at mix.wvu.edu
Cited by 215

[HTML][HTML] Cytokine signaling in multiple sclerosis and its therapeutic applications

P Palle, KL Monaghan, SM Milne, ECK Wan - Medical sciences, 2017 - mdpi.com
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults.
The etiology of MS is not known but it is widely accepted that it is autoimmune in nature. …

[HTML][HTML] The role of granulocyte-macrophage colony-stimulating factor in murine models of multiple sclerosis

KL Monaghan, ECK Wan - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is an immune-mediated disease that predominantly impacts the central
nervous system (CNS). Animal models have been used to elucidate the underpinnings of …

Clinical findings, diagnostics and outcome in 33 cats with adrenal neoplasia (2002–2013)

…, E Appleman, KN Monaghan… - Journal of feline …, 2016 - journals.sagepub.com
Objectives The objective of this retrospective study was to describe the clinical signs and
diagnostic findings in cats with histopathologically confirmed adrenal neoplasms, and to assess …

Tetramerization of STAT5 promotes autoimmune-mediated neuroinflammation

KL Monaghan, D Aesoph, AG Ammer… - Proceedings of the …, 2021 - National Acad Sciences
Signal tranducer and activator of transcription 5 (STAT5) plays a critical role in mediating
cellular responses following cytokine stimulation. STAT proteins critically signal via the …

[HTML][HTML] Monocytes and monocyte-derived antigen-presenting cells have distinct gene signatures in experimental model of multiple sclerosis

KL Monaghan, W Zheng, G Hu, ECK Wan - Frontiers in immunology, 2019 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory disease mediated by a complex interaction
between the autoreactive lymphocytes and the effector myeloid cells within the central …

Feline acute kidney injury: 1. Pathophysiology, etiology and etiology-specific management considerations

K Monaghan, B Nolan… - Journal of feline medicine …, 2012 - journals.sagepub.com
Practical relevance: Acute kidney injury (AKI) is a frequently recognized disease process in
cats that requires immediate and aggressive intervention. A thorough understanding of the …

Dose-Specific Intratumoral GM-CSF Modulates Breast Tumor Oxygenation and Antitumor Immunity

…, L Wang, RC O'Connell, KL Monaghan… - The Journal of …, 2023 - journals.aai.org
GM-CSF has been employed as an adjuvant to cancer immunotherapy with mixed results
based on dosage. We previously showed that GM-CSF regulated tumor angiogenesis by …

Ischemic stroke alters immune cell niche and chemokine profile in mice independent of spontaneous bacterial infection

BY Farris, KL Monaghan, W Zheng… - Immunity …, 2019 - Wiley Online Library
Introduction Stroke‐associated pneumonia (SAP) is a major cause of mortality in patients
who have suffered from severe ischemic stroke. Although multifactorial in nature, stroke‐…

Ampicillin pharmacokinetics in azotemic and healthy dogs

KN Monaghan, MA Labato… - Journal of Veterinary …, 2021 - Wiley Online Library
Background Little is known about effects of factors such as kidney disease, affecting ampicillin
pharmacokinetics in dogs. Objectives Determine the pharmacokinetics of ampicillin after a …

Feline acute kidney injury: 2. Approach to diagnosis, treatment and prognosis

K Monaghan, B Nolan… - Journal of Feline Medicine …, 2012 - journals.sagepub.com
Practical relevance: Feline acute kidney injury (AKI) is a commonly recognized problem in
small animal practice that requires prompt diagnosis and directed therapy. There are many …