User profiles for Keyvan Karkouti

Keyvan Karkouti

University of Toronto
Verified email at uhn.ca
Cited by 15197

Acute kidney injury after cardiac surgery: focus on modifiable risk factors

K Karkouti, DN Wijeysundera, TM Yau, JL Callum… - Circulation, 2009 - Am Heart Assoc
Background— Acute kidney injury (AKI) after cardiac surgery is a major health issue.
Lacking effective therapies, risk factor modification may offer a means of preventing this …

Risk associated with preoperative anemia in noncardiac surgery: a single-center cohort study

WS Beattie, K Karkouti, DN Wijeysundera… - The Journal of the …, 2009 - pubs.asahq.org
Background Preoperative anemia is an important risk factor for perioperative red blood cell
transfusions and has been shown to be independently associated with adverse outcomes …

The independent association of massive blood loss with mortality in cardiac surgery

K Karkouti, DN Wijeysundera, TM Yau, WS Beattie… - …, 2004 - Wiley Online Library
BACKGROUND: Although the association between massive perioperative blood loss (MBL)
and adverse outcomes is well recognized, it is unclear whether MBL is an independent risk …

Risk associated with preoperative anemia in cardiac surgery: a multicenter cohort study

K Karkouti, DN Wijeysundera, WS Beattie - Circulation, 2008 - Am Heart Assoc
Background— Preoperative anemia is an important risk factor for perioperative red blood
cell transfusions, which are associated with postoperative morbidity and mortality. Whether …

[HTML][HTML] Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery

T Doenst, D Wijeysundera, K Karkouti… - The Journal of thoracic …, 2005 - Elsevier
BACKGROUND: Hyperglycemia is commonly present in the perioperative period in patients
undergoing cardiac surgery, even during administration of insulin. A direct relationship …

Derivation and validation of a simplified predictive index for renal replacement therapy after cardiac surgery

DN Wijeysundera, K Karkouti, JY Dupuis, V Rao… - Jama, 2007 - jamanetwork.com
ContextA predictive index for renal replacement therapy (RRT; hemodialysis or continuous
venovenous hemodiafiltration) after cardiac surgery may improve clinical decision making …

A propensity score case‐control comparison of aprotinin and tranexamic acid in high‐transfusion‐risk cardiac surgery

K Karkouti, WS Beattie, KM Dattilo, SA McCluskey… - …, 2006 - Wiley Online Library
BACKGROUND: Cardiac surgery with cardiopulmonary bypass may result in excessive
fibrinolysis and platelet (PLT) dysfunction, resulting in impaired hemostasis and excessive blood …

Hyperchloremia after noncardiac surgery is independently associated with increased morbidity and mortality: a propensity-matched cohort study

SA McCluskey, K Karkouti, D Wijeysundera… - Anesthesia & …, 2013 - journals.lww.com
BACKGROUND: The use of normal saline is associated with hyperchloremic metabolic
acidosis. In this study, we sought to determine the incidence of acute postoperative …

[HTML][HTML] Universal definition of perioperative bleeding in adult cardiac surgery

…, S Aronson, W Dietrich, A Hofmann, K Karkouti… - The Journal of thoracic …, 2014 - Elsevier
Objectives Perioperative bleeding is common among patients undergoing cardiac surgery;
however, the definition of perioperative bleeding is variable and lacks standardization. We …

Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study

…, S Choi, K Flores, S Au, WS Beattie, K Karkouti… - The Lancet, 2018 - thelancet.com
Background Functional capacity is an important component of risk assessment for major
surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain …