Objectives : We sought to conduct a systematic review and meta-analysis of the cardiovascular
risk associated with the metabolic syndrome as defined by the 2001 National Cholesterol …

In pharmacoepidemiology, routinely collected data from electronic health records (including
primary care databases, registries, and administrative healthcare claims) are a resource for …

BACKGROUND: Exercise-based cardiac rehabilitation (CR) remains an underused tool for
secondary prevention post–myocardial infarction (MI). In part, this arises from uncertainty …

New oral anticoagulants, including apixaban, dabigatran, and rivaroxaban, have been
developed as alternatives to warfarin, the standard oral anticoagulation therapy for patients with …

Atrial fibrillation (AF) is 1 of the most clinically diagnosed cardiac disturbances but little is
known about its risk factors. Previous epidemiologic studies have reported on the association …

Background: Many placebo-controlled trials have demonstrated the efficacy of individual
pharmacotherapies approved for smoking cessation. However, few direct or indirect …

Objectives : This study sought to determine the current effectiveness and safety of
sympathetic renal denervation (RDN) for resistant hypertension. Background : RDN is a novel …

Background: Women with a history of certain pregnancy complications are at higher risk for
cardiovascular (CVD) disease. However, most clinical guidelines only recommend …

BACKGROUND: Aerobic exercise is a common nonpharmacological intervention for the
management of obesity. However, the efficacy of isolated aerobic exercise at promoting weight …

Objective To determine if the use of pioglitazone is associated with an increased risk of incident
bladder cancer in people with type 2 diabetes. Design Retrospective cohort study using …