This study was carried out to determine whether the minimal important difference, in evaluative
quality of life instruments which use a 7-point scale, is similar across individual domains …

When little or no data directly comparing two treatments are available, investigators often
rely on indirect comparisons from studies testing the treatments against a control or placebo. …

The Paediatric Asthma Quality of Life Questionnaire contains 23 items that children with
asthma have identified as troublesome in their daily lives. The aim was to evaluate the …

Background: Understanding the risk factors for ventilator-associated pneumonia can help to
assess prognosis and devise and test preventive strategies. Objective: To examine the …

Study Design In an 8-wk unblinded single cohort study, patients with adequately controlled
asthma symptoms continued on their established treatment regimens. Patients whose …

Background The efficacy of prophylaxis against stress ulcers in preventing gastrointestinal
bleeding in critically ill patients has led to its widespread use. The side effects and cost of …

To evaluate the attributable morbidity and mortality of ventilator-associated pneumonia (VAP)
in intensive care unit (ICU) patients, we conducted a prospective, matched cohort study. …

Background Critically ill patients who require mechanical ventilation are at increased risk for
gastrointestinal bleeding from stress ulcers. There are conflicting data on the effect of …

Purpose. —To resolve discrepancies in previous systematic overviews and provide estimates
of the effect of stress ulcer prophylaxis on gastrointestinal bleeding, pneumonia, and …

Objective: To review the effectiveness of primary prevention strategies aimed at delaying
sexual intercourse, improving use of birth control, and reducing incidence of unintended …