Carfilzomib and dexamethasone versus bortezomib and dexamethasone for patients with relapsed or refractory multiple myeloma (ENDEAVOR): a randomised …

…, V Goranova-Marinova, A Schwarer, L Minuk… - The Lancet …, 2016 - thelancet.com
Background Bortezomib with dexamethasone is a standard treatment option for relapsed or
refractory multiple myeloma. Carfilzomib with dexamethasone has shown promising activity …

Carfilzomib or bortezomib in relapsed or refractory multiple myeloma (ENDEAVOR): an interim overall survival analysis of an open-label, randomised, phase 3 trial

…, R Hajek, K Weisel, V Hungria, L Minuk… - The Lancet …, 2017 - thelancet.com
Background The phase 3 ENDEAVOR trial was a head-to-head comparison of two
proteasome inhibitors in patients with relapsed or refractory multiple myeloma. Progression-free …

[HTML][HTML] Health-related quality-of-life in patients with newly diagnosed multiple myeloma in the FIRST trial: lenalidomide plus low-dose dexamethasone versus …

M Delforge, L Minuk, JC Eisenmann, B Arnulf… - …, 2015 - ncbi.nlm.nih.gov
We compared the health-related quality-of-life of patients with newly diagnosed multiple
myeloma aged over 65 years or transplant-ineligible in the pivotal, phase III FIRST trial. Patients …

Addition of elotuzumab to lenalidomide and dexamethasone for patients with newly diagnosed, transplantation ineligible multiple myeloma (ELOQUENT-1): an open …

…, A Grigg, B De Prijck, M Louzada, L Minuk… - The Lancet …, 2022 - thelancet.com
Background Elotuzumab plus lenalidomide and dexamethasone has shown improved
progression-free and overall survival versus lenalidomide and dexamethasone in patients with …

[PDF][PDF] Decreased hepatocyte membrane potential differences and GABAa‐β3 expression in human hepatocellular carcinoma

GY Minuk, M Zhang, Y Gong, L Minuk, H Dienes… - …, 2007 - Wiley Online Library
To determine whether hepatocyte membrane potential differences (PDs) are depolarized in
human HCC and whether depolarization is associated with changes in GABA A receptor …

Desmopressin responsiveness at a capped dose of 15 μg in type 1 von Willebrand disease and mild hemophilia A

…, L Laudenbach, S Schembri, L Minuk - Blood Coagulation & …, 2014 - journals.lww.com
Desmopressin (DDAVP) is commonly used in the treatment of patients with type 1 von
Willebrand disease (VWD) and mild hemophilia A. A patient's responsiveness to DDAVP based …

[HTML][HTML] Prophylaxis in older Canadian adults with hemophilia A: lessons and more questions

SC Jackson, M Yang, L Minuk, M Sholzberg, J St-Louis… - BMC hematology, 2015 - Springer
Background Although prophylaxis is a standard of care for young children in developed
countries, known to reduce the severity of hemophilic arthropathy, older adults with existing …

[HTML][HTML] Normal levels of protein C and protein S tested in the acute phase of a venous thromboembolic event are not falsely elevated

L Minuk, A Lazo-Langner, J Kovacs, M Robbins… - Thrombosis …, 2010 - Springer
Background Protein C (PC) and protein S (PS) determination is part of the thrombophilia
investigation in patients with idiopathic venous thromboembolism (VTE). Based on scarce …

Treatment of Hodgkin lymphoma with adriamycin, bleomycin, vinblastine and dacarbazine without routine granulocyte-colony stimulating factor support does not …

LA Minuk, K Monkman, IH Chin-Yee… - Leukemia & …, 2012 - Taylor & Francis
Although patients with Hodgkin lymphoma treated with adriamycin, bleomycin, vinblastine
and dacarbazine (ABVD) chemotherapy frequently develop neutropenia, febrile neutropenia …

The pandemic H1N1 influenza vaccine results in low rates of seroconversion for patients with hematological malignancies

…, A Lazo-Langner, BH Chin-Yee, LA Minuk - Leukemia & …, 2011 - Taylor & Francis
Patients with hematological malignancies are at increased risk of influenza and its complications,
but evidence for the efficacy of influenza vaccination in this population is limited. We …