[HTML][HTML] Folic acid supplementation promotes mammary tumor progression in a rat model

S Deghan Manshadi, L Ishiguro, KJ Sohn, A Medline… - PloS one, 2014 - journals.plos.org
Folic acid supplementation may prevent the development of cancer in normal tissues but may
promote the progression of established (pre)neoplastic lesions. However, whether or not …

Maternal folic acid supplementation modulates DNA methylation and gene expression in the rat offspring in a gestation period-dependent and organ-specific manner

A Ly, L Ishiguro, D Kim, D Im, SE Kim, KJ Sohn… - The Journal of nutritional …, 2016 - Elsevier
Maternal folic acid supplementation can alter DNA methylation and gene expression in the
developing fetus, which may confer disease susceptibility later in life. We determined which …

Immaterial labors: Ishiguro, class, and affect

L Fluet - Novel: A Forum on Fiction, 2007 - JSTOR
… And yet, as I suggest in what follows, Ishiguro's protagonists talk about something like class
… I suggest ultimately that immaterial laborers have no future in Ishiguro's novels; but that this …

[HTML][HTML] Pivoting data and analytic capacity to support Ontario's COVID-19 response

…, A Guttmann, MM Ho, L Ishiguro… - … Journal of Population …, 2020 - ncbi.nlm.nih.gov
Methods We describe how ICES, an independent not-for-profit research and analytic institute
in Ontario, Canada, pivoted existing research infrastructure and engaged health system …

Estimated surge in hospital and intensive care admission because of the coronavirus disease 2019 pandemic in the Greater Toronto Area, Canada: a mathematical …

…, MJ Schull, V Pequegnat, A Lee, L Ishiguro… - … Open Access Journal, 2020 - cmajopen.ca
Background: In pandemics, local hospitals need to anticipate a surge in health care needs.
We examined the modelled surge because of the coronavirus disease 2019 (COVID-19) …

[PDF][PDF] Increasing access to health administrative data with ICES data & analytic services

L Ishiguro, R Saskin, MJ Vermeulen, E Yates… - Healthc Q, 2016 - scholar.archive.org
The Institute for Clinical Evaluative Sciences (ICES) is one of only a few organizations in
Ontario permitted to access, link and analyze health administrative data for the purpose of …

[HTML][HTML] Supporting policy and practice in Ontario through ICES'applied health research question (AHRQ) program

L Ishiguro, DA An, L Plumptre, J Paul… - … Journal of Population …, 2021 - ncbi.nlm.nih.gov
ICES upholds a strong reputation for generating high-quality evidence to inform policy and
practice through its collaborations with a broad range of health system stakeholders including …

Folic acid supplementation adversely affects chemosensitivity of colon cancer cells to 5-fluorouracil

L Ishiguro, M Yang, KJ Sohn, CJ Streutker… - Nutrition and …, 2016 - Taylor & Francis
Folic acid (FA) fortification and widespread supplemental use have significantly increased
folate status in North America. Furthermore, >50% of colorectal cancer patients use FA …

An Interview with Kazuo Ishiguro

A Vorda, K Herzinger, K Ishiguro - Mississippi Review, 1991 - JSTOR
Ishiguro was in town as a guest speaker for the literary workshops … Kazuo Ishiguro: Not really.
It's partly because they knew I … If we look around for writers who sound a bit like Ishiguro, it …

[HTML][HTML] Examination of high-cost patients in Ontario

E Homenauth, E Graves, L Ishiguro, R Saskin… - International Journal of …, 2018 - ijpds.org
Results In the top 5% of high-cost users, there were 729,870 patients who accounted for
$20,179,208,348 of total healthcare spending in 2012/13, with the highest percentage of …