Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995–2005: a population-based study

LL Lipscombe, JE Hux - The Lancet, 2007 - thelancet.com
Background The prevalence of diabetes has been increasing greatly, but WHO's predicted
39% rise in the global rate of diabetes from 2000 to 2030 might be an underestimate. We …

Thiazolidinediones and cardiovascular outcomes in older patients with diabetes

LL Lipscombe, T Gomes, LE Lévesque, JE Hux… - Jama, 2007 - jamanetwork.com
ContextThiazolidinediones (TZDs), used to treat type 2 diabetes, are associated with an
excess risk of congestive heart failure and possibly acute myocardial infarction. However, the …

Trends in incidence of diabetes in pregnancy and serious perinatal outcomes: a large, population-based study in Ontario, Canada, 1996–2010

…, GL Booth, AS Bierman, LL Lipscombe - Diabetes …, 2014 - Am Diabetes Assoc
OBJECTIVE Women with diabetes in pregnancy have high rates of pregnancy complications.
Our aims were to explore trends in the incidence of diabetes in pregnancy and examine …

The risk of hip fractures in older individuals with diabetes: a population-based study

LL Lipscombe, SA Jamal, GL Booth… - Diabetes care, 2007 - Am Diabetes Assoc
OBJECTIVE—Compared with men and women without diabetes, individuals with type 2
diabetes have higher bone mineral density (BMD). However, they may still be at increased risk …

[HTML][HTML] All-cause mortality and serious cardiovascular events in people with hip and knee osteoarthritis: a population based cohort study

…, PJ Harvey, B Ravi, I Stanaitis, LL Lipscombe - PloS one, 2014 - journals.plos.org
Background Because individuals with osteoarthritis (OA) avoid physical activities that exacerbate
symptoms, potentially increasing risk for cardiovascular disease (CVD) and death, we …

Prevalence and incidence of hypertension from 1995 to 2005: a population-based study

K Tu, Z Chen, LL Lipscombe - Cmaj, 2008 - Can Med Assoc
Background: Researchers have predicted that there will be a relative increase of 24% in the
prevalence of hypertension in developed countries from 2000 to 2025. Hypertension is a …

[PDF][PDF] Metformin use and all-cause and prostate cancer-specific mortality among men with diabetes

D Margel, DR Urbach, LL Lipscombe, CM Bell… - J Clin …, 2013 - bendixcarstensen.com
Lipscombe, Chaim M. Bell, Girish Kulkarni, Peter C. Austin, and Neil Fleshner … Lipscombe,
Chaim M. Bell, Girish Kulkarni, and … Azoulay L, Dell’Aniello S, Gagnon B, et al: Metformin …

The impact of diabetes on survival following breast cancer

LL Lipscombe, PJ Goodwin, B Zinman… - Breast cancer research …, 2008 - Springer
Purpose It has been suggested that type 2 diabetes may affect breast cancer prognosis,
possibly due to increased diabetes-related comorbidity, or direct effects of insulin resistance and/…

Diabetes, obesity, and cancer—pathophysiology and clinical implications

IC Lega, LL Lipscombe - Endocrine reviews, 2020 - academic.oup.com
Obesity and diabetes have both been associated with an increased risk of cancer. In the face
of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer rates. …

Metformin in women with type 2 diabetes in pregnancy (MiTy): a multicentre, international, randomised, placebo-controlled trial

…, E Hutton, AB Armson, LL Lipscombe… - The Lancet Diabetes & …, 2020 - thelancet.com
Background Although metformin is increasingly being used in women with type 2 diabetes
during pregnancy, little data exist on the benefits and harms of metformin use on pregnancy …