User profiles for Luanne Metz
 | Luanne Marie MetzUniversity of Calgary Verified email at ahs.ca Cited by 19208 |
Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”
New diagnostic criteria for multiple sclerosis integrating magnetic resonance image
assessment with clinical and other paraclinical methods were introduced in 2001. The “McDonald …
assessment with clinical and other paraclinical methods were introduced in 2001. The “McDonald …
A full genome search in multiple sclerosis
The aetiology of multiple sclerosis (MS) is uncertain. There is strong circumstantial evidence
to indicate it is an autoimmune complex trait 1–3 . Risks for first degree relatives are …
to indicate it is an autoimmune complex trait 1–3 . Risks for first degree relatives are …
Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis
V Brundula, NB Rewcastle, LM Metz, CC Bernard… - Brain, 2002 - academic.oup.com
Multiple sclerosis is characterized by the infiltration of leukocytes into the CNS. As matrix
metalloproteinases (MMPs) facilitate the passage of leukocytes across matrix barriers, we …
metalloproteinases (MMPs) facilitate the passage of leukocytes across matrix barriers, we …
The promise of minocycline in neurology
The capacity of minocycline to alleviate disease for several neurological disorders in animals
is increasingly being recognised. Indeed, that one drug alone can attenuate the severity of …
is increasingly being recognised. Indeed, that one drug alone can attenuate the severity of …
Endocrine disrupting chemicals and immune responses: A focus on bisphenol-A and its potential mechanisms
Endocrine disrupting chemicals (EDCs) have become of concern for a variety f health issues.
Due to their effects on the endocrine system they have been thoroughly examined with …
Due to their effects on the endocrine system they have been thoroughly examined with …
Long-term medical conditions and major depression: strength of association for specific conditions in the general population
Background: The prevalence of major depression (MD) in persons with nonpsychiatric medical
conditions is an indicator of clinical need in those groups, an indicator of the feasibility of …
conditions is an indicator of clinical need in those groups, an indicator of the feasibility of …
Regional variation of multiple sclerosis prevalence in Canada
CA Beck, LM Metz, LW Svenson… - Multiple Sclerosis …, 2005 - journals.sagepub.com
Objective: To describe the regional distribution of multiple sclerosis (MS) prevalence in
Canada, controlling for age and sex. Methods: This study used data from the Canadian …
Canada, controlling for age and sex. Methods: This study used data from the Canadian …
[HTML][HTML] Trial of minocycline in a clinically isolated syndrome of multiple sclerosis
Background On the basis of encouraging preliminary results, we conducted a randomized,
controlled trial to determine whether minocycline reduces the risk of conversion from a first …
controlled trial to determine whether minocycline reduces the risk of conversion from a first …
Biopsychosocial correlates of lifetime major depression in a multiple sclerosis population
The objective of this paper was to evaluate the lifetime and point prevalence of major
depression in a population-based Multiple Sclerosis (MS) clinic sample, and to describe …
depression in a population-based Multiple Sclerosis (MS) clinic sample, and to describe …
Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators
The matrix metalloproteinases (MMPs) are implicated in the pathology of multiple sclerosis (MS).
This review summarizes the consequences of upregulation of MMP members in MS as …
This review summarizes the consequences of upregulation of MMP members in MS as …