[HTML][HTML] A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity
…, N Almamlouk, Y Chen, M Chassé, M Durand… - Nature medicine, 2021 - nature.com
To identify circulating proteins influencing Coronavirus Disease 2019 (COVID-19) susceptibility
and severity, we undertook a two-sample Mendelian randomization (MR) study, rapidly …
and severity, we undertook a two-sample Mendelian randomization (MR) study, rapidly …
Association between HIV infection, antiretroviral therapy, and risk of acute myocardial infarction: a cohort and nested case–control study using Quebec's public health …
M Durand, O Sheehy, JG Baril, J Lelorier… - JAIDS Journal of …, 2011 - journals.lww.com
Background: Morbidity associated with cardiovascular disease is increasing in the HIV-infected
population. We aimed to study the impact of HIV and of antiretrovirals on acute …
population. We aimed to study the impact of HIV and of antiretrovirals on acute …
Integrated immunovirological profiling validates plasma SARS-CoV-2 RNA as an early predictor of COVID-19 mortality
Despite advances in COVID-19 management, identifying patients evolving toward death
remains challenging. To identify early predictors of mortality within 60 days of symptom onset (…
remains challenging. To identify early predictors of mortality within 60 days of symptom onset (…
[HTML][HTML] Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial
…, EL Falcone, R Jamal, ML Luong, M Durand… - The Lancet …, 2021 - thelancet.com
Background Elevated proinflammatory cytokines are associated with greater COVID-19 severity.
We aimed to assess safety and efficacy of sarilumab, an interleukin-6 receptor inhibitor, …
We aimed to assess safety and efficacy of sarilumab, an interleukin-6 receptor inhibitor, …
[HTML][HTML] Remdesivir for the treatment of patients in hospital with COVID-19 in Canada: a randomized controlled trial
…, J Douglas, C Downey, E Duan, E Duceppe, M Durand… - Cmaj, 2022 - Can Med Assoc
Background: The role of remdesivir in the treatment of patients in hospital with COVID-19
remains ill defined in a global context. The World Health Organization Solidarity randomized …
remains ill defined in a global context. The World Health Organization Solidarity randomized …
Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis
…, D Chateau, LE Targownik, A Gershon, M Durand… - Gut, 2014 - gut.bmj.com
Objective Previous observational studies suggest that the use of proton pump inhibitors (PPIs)
may increase the risk of hospitalisation for community-acquired pneumonia (HCAP). …
may increase the risk of hospitalisation for community-acquired pneumonia (HCAP). …
[HTML][HTML] Comorbidity is more common and occurs earlier in persons living with HIV than in HIV-uninfected matched controls, aged 50 years and older: a cross …
RA Maciel, HM Klück, M Durand, E Sprinz - International Journal of …, 2018 - Elsevier
Objectives At present, data are limited on the comorbidity profiles associated with aging people
with HIV in the developing world, where most such people live. The aim of this study was …
with HIV in the developing world, where most such people live. The aim of this study was …
[HTML][HTML] Covid-19 vaccine immunogenicity in people living with HIV-1
…, V Martel-Laferrière, B Trottier, J Richard, M Durand… - Vaccine, 2022 - Elsevier
Introduction COVID-19 vaccine efficacy has been evaluated in large clinical trials and in real-world
situation. Although they have proven to be very effective in the general population, …
situation. Although they have proven to be very effective in the general population, …
Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study
…, M Dahl, CR Dormuth, KK Clemens, M Durand… - bmj, 2016 - bmj.com
Objective To determine whether the use of incretin based drugs compared with sulfonylureas
is associated with an increased risk of incident pancreatic cancer in people with type 2 …
is associated with an increased risk of incident pancreatic cancer in people with type 2 …
Association between incretin-based drugs and the risk of acute pancreatitis
…, CR Dormuth, KK Clemens, M Durand… - JAMA internal …, 2016 - jamanetwork.com
Importance The association between incretin-based drugs, such as dipeptidyl peptidase 4 (DPP-4)
inhibitors and glucagon-like peptide 1 (GLP-1) agonists, and acute pancreatitis is …
inhibitors and glucagon-like peptide 1 (GLP-1) agonists, and acute pancreatitis is …