Background: With the legalization of cannabis in Canada, young adults, who are already at
risk of automobile crashes, may increase their use of cannabis, which may further increase …

Delta-8-tetrahydrocannabinol (Δ8-THC) has emerged as a new retail cannabinoid product
in the US This study queried Δ8-THC users about product use characteristics and self-…

Objective: To investigate the safety and effectiveness of medical cannabis (MC) in the real-world
clinical practice setting. Design: A 4-year prospective noncomparative registry of adult …

Introduction: Clinical trials remain the gold standard for evaluating efficacy, but there is
increasing interest in using real-world evidence (RWE) to inform health care decision making. …

Objective Many patients with fibromyalgia (FM) report using cannabis as a strategy to
improve pain. Given that pain often co‐occurs with symptoms of anxiety and depression (ie, …

Introduction: Despite increasing demand for data, little is known about the authorization
patterns, safety, and effectiveness of medical cannabis products. Materials and Methods: We …

The present study sought to determine the effects of cannabinol (CBN) alone and in combination
with cannabidiol (CBD) on sleep quality. This was a double-blind, randomized, placebo-…

Background Use of medical cannabis is increasing among older adults. However, few
investigations have examined cannabis use in this population. Methods We assessed the …

Introduction Published data on the safety of natural medical cannabis (MC) when used in the
real-world clinical practice setting are lacking. This study aimed to describe adverse events …

Objective To evaluate the effectiveness of Δ9-tetrahydrocannabinol (dronabinol [DRO]) as
an add-on treatment in patients with refractory chronic pain (CP). Methods An exploratory …