As detected by cross‐sectional imaging, severe muscle depletion, which is termed sarcopenia,
holds promise for prognostication in patients with cirrhosis. Our aims were to describe the …

The (–) enantiomer of 3′–thiacytidine (lamivudine) has been found to be a potent inhibitor
of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) replication. Mutation of …

An increasing number of patients with hepatocellular carcinoma (HCC) are undergoing
evaluation for listing for liver transplantation. Criteria for selection require ongoing review for …

METHODS: This is an international cohort study including patients with paired LSM/hepatic
venous pressure gradient (HVPG), LSM≥ 10 kPa, and no previous decompensation. Portal …

Background. We report long-term outcomes and side effects after transplantation for hepatocellular
carcinoma (HCC) using de novo, sirolimus-based immunosuppression (IS). Methods. …

Background: Conventional treatment of autoimmune hepatitis consists of either prednisone
alone or in combination with azathioprine. Ten to 20% of patients do not respond to or are …

Chronic hepatitis B (CHB) is a dynamic disease that is influenced by host and virological
factors. The management of CHB has become more complex with the increasing use of long-…

OBJECTIVES: Liver transplantation for alcoholic liver disease (ALD) can be complicated by
abusive or “problem” drinking (PD) after transplant. There are limited data for evaluating the …

Detection of advanced fibrosis in nonalcoholic fatty liver disease (NAFLD) is essential for
stratifying patients according to the risk of liver‐related morbidity. Noninvasive methods such as …

Hepatitis B virus (HBV) infection is an important public health problem in Canada. In keeping
with evolving evidence and understanding of HBV pathogenesis, the Canadian Association …