The field of antibiotic drug discovery and the monitoring of new antibiotic resistance elements
have yet to fully exploit the power of the genome revolution. Despite the fact that the first …

Background Concurrent chemoradiotherapy followed by adjuvant chemotherapy (CRT-A) is
often the regimen of choice in locoregionally advanced nasopharyngeal carcinoma (NPC). …

In the United States, Mycobacterium avium complex (MAC) and Mycobacterium abscessus
are the two predominant causes of nontuberculous mycobacterial pulmonary disease (NTM-…

Slowly growing nontuberculous mycobacteria (NTM) comprise a diverse group of environmental
organisms, many of which are important human pathogens. The most common and well-…

Outpatient parenteral antimicrobial therapy (OPAT) is a safe and effective alternative to
hospitalization for many patients with infectious diseases. The objective of this study was to …

Edeines are atypical cationic peptides produced by Brevibacillus brevis Vm4 with broad-spectrum
antimicrobial activity. These linear nonribosomal peptides bind to the 30S ribosomal …

Tuberculin skin tests and IGRAs detect evidence of immunity to TB antigens but cannot
distinguish TB infection from disease. Negative results do not exclude TB disease, as false …

The article discusses on the rare bleeding disorder acquired haemophilia A (AHA). The
diagnosis of the disease confirms the inhibitory antibodies and low factor VIII activity detected by …

Background The clinical course of nontuberculous mycobacterial pulmonary disease (NTM-PD)
can be variable and difficult to predict. Recently, the BACES score was developed as a …

Background There is growing interest in using high-dose rifamycin (HDR) regimens in TB
treatment, but the safety and efficacy of HDR regimens remain uncertain. We performed a …