Objectives To evaluate the current state of evidence for antimicrobial stewardship interventions
in the critical care unit. Methods We performed a systematic search of OVID MEDLINE, …

Objective.We aimed to rigorously evaluate the impact of prospective audit and feedback on
broad-spectrum antimicrobial use among critical care patients.Design.Prospective, controlled …

Background Prophylactic antimicrobial therapy is frequently prescribed for acute aspiration
pneumonitis, with the intent of preventing the development of aspiration pneumonia. However…

Rationale The impact of hospital length of stay (LOS) on the distribution and susceptibility of
Gram negative bacteria (GNB) causing infection in burn patients remains unexplored. …

Introduction Empiric antimicrobial selection for critical care infections must balance the need
for timely adequate coverage with the resistance pressure exerted by broadspectrum agents…

Burn patients are at high risk for infections; however, common indicators of infection are
unreliable in this population and can lead to unnecessary use of antibiotics. The study objective …

BACKGROUND: The optimal duration of antibiotic treatment for bloodstream infections is
unknown and understudied.METHODS: A retrospective cohort study of critically ill patients with …

Objective:To assess whether a self-reported β-lactam allergy is associated with an increased
risk of surgical site infection (SSI) across a broad range of procedures and to determine …

Antimicrobial stewardship has been defined as the limitation of inappropriate use of antimicrobials
while optimizing the selection, dosing, route, and duration of antimicrobial therapy to …

A successful day 3 intensive care unit antimicrobial audit-andfeedback program was
expanded hospital-wide, with high rates of orders reviewed, suggestions made, and advice …