User profiles for Mark Hartman

Mark L Hartman

Eli Lilly and Company
Verified email at lilly.com
Cited by 9805

[HTML][HTML] Triple–hormone-receptor agonist retatrutide for obesity—a phase 2 trial

…, A Haupt, Z Milicevic, ML Hartman - … England Journal of …, 2023 - Mass Medical Soc
Background Retatrutide (LY3437943) is an agonist of the glucose-dependent insulinotropic
polypeptide, glucagon-like peptide 1, and glucagon receptors. Its dose–response …

Sensitivity and specificity of six tests for the diagnosis of adult GH deficiency

…, DL Kleinberg, JJ Chipman, ML Hartman - The Journal of …, 2002 - academic.oup.com
Although the use of the insulin tolerance test (ITT) for the diagnosis of adult GH deficiency is
well established, diagnostic peak GH cut-points for other commonly used GH stimulation …

Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group …

…, Y Du, J Lou, S Gurbuz, MK Thomas, ML Hartman… - The Lancet, 2023 - thelancet.com
Background According to current consensus guidelines for type 2 diabetes management,
bodyweight management is as important as attaining glycaemic targets. Retatrutide, a single …

Augmented growth hormone (GH) secretory burst frequency and amplitude mediate enhanced GH secretion during a two-day fast in normal men

ML Hartman, JD Veldhuis, ML Johnson… - The Journal of …, 1992 - academic.oup.com
Serum GH concentrations are increased in fasted or malnourished human subjects. We
investigated the dynamic mechanisms underlying this phenomenon in nine normal men by …

Which patients do not require a GH stimulation test for the diagnosis of adult GH deficiency?

ML Hartman, BJ Crowe, BMK Biller… - The Journal of …, 2002 - academic.oup.com
Adult GH deficiency (GHD) is currently diagnosed in patients with either a history of childhood-onset
GHD or acquired hypothalamic-pituitary disease by GH stimulation testing. However…

Cortisol and growth hormone responses to exercise at different times of day

…, KS Pieper, A Weltman, ML Hartman - The Journal of …, 2001 - academic.oup.com
Exercise of appropriate intensity is a potent stimulus for GH and cortisol secretion. Circadian
and diurnal rhythms may modulate the GH and cortisol responses to exercise, but nutrition, …

Thirty-second sampling of plasma growth hormone in man: correlation with sleep stages

RW Holl, ML Hartman, JD Veldhuis… - The Journal of …, 1991 - academic.oup.com
Both fasting and sleep increase the secretion of human GH and, therefore, might explain its
predominantly nocturnal release. To study the precise temporal relationship between GH …

Growth hormone release during acute and chronic aerobic and resistance exercise: recent findings

L Wideman, JY Weltman, ML Hartman, JD Veldhuis… - Sports medicine, 2002 - Springer
Exercise is a potent physiological stimulus for growth hormone (GH) secretion, and both
aerobic and resistance exercise result in significant, acute increases in GH secretion. Contrary …

Effects of novel dual GIP and GLP-1 receptor agonist tirzepatide on biomarkers of nonalcoholic steatohepatitis in patients with type 2 diabetes

ML Hartman, AJ Sanyal, R Loomba, JM Wilson… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE To determine the effect of tirzepatide, a dual agonist of glucose-dependent
insulinotropic polypeptide and glucagon-like peptide 1 receptors, on biomarkers of nonalcoholic …

The use of anthropometric and dual‐energy X‐ray absorptiometry (DXA) measures to estimate total abdominal and abdominal visceral fat in men and women

…, JE Riblett, MO Thorner, ML Hartman… - Obesity …, 1999 - Wiley Online Library
The Use of Anthropometric and Dualâ•’Energy Xâ•’ray Absorptiometry (DXA) Measures to
Estimate Total Abdominal and Abdo Page 1 The Use of Anthropometric and Dual-Energy X-…