User profiles for Matthew Muller

Matthew Muller

Associate Professor of Medicine, University of Toronto
Verified email at smh.ca
Cited by 6652

Human immunopathogenesis of severe acute respiratory syndrome (SARS)

MJ Cameron, JF Bermejo-Martin, A Danesh, MP Muller… - Virus research, 2008 - Elsevier
Progressive immune-associated injury is a hallmark of severe acute respiratory syndrome (SARS).
Viral evasion of innate immunity, hypercytokinemia and systemic immunopathology in …

Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extended-spectrum beta-lactamase involved in an outbreak in long-term-care …

…, S Christianson, A McGeer, MP Muller… - Antimicrobial agents …, 2004 - Am Soc Microbiol
A major outbreak involving an Escherichia coli strain that was resistant to expanded-spectrum
cephalosporins occurred in Toronto and surrounding regions in 2000 to 2002. We report …

Development of a triage protocol for critical care during an influenza pandemic

…, RS Wax, T Cook, NM Lazar, MS Herridge, MP Muller… - Cmaj, 2006 - Can Med Assoc
Background: The recent outbreaks of avian influenza (H5N1) have placed a renewed
emphasis on preparing for an influenza pandemic in humans. Of particular concern in this …

One-year outcomes and health care utilization in survivors of severe acute respiratory syndrome

…, M Louie, M Loeb, WL Gold, MP Muller… - Archives of internal …, 2007 - jamanetwork.com
Background Severe Acute Respiratory Syndrome (SARS) became a global epidemic in
2003. Comprehensive information on 1-year outcomes and health care utilization is lacking. …

Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory …

…, JF Bermejo-Martin, CM Cameron, MP Muller… - Journal of …, 2007 - Am Soc Microbiol
It is not understood how immune inflammation influences the pathogenesis of severe acute
respiratory syndrome (SARS). One area of strong controversy is the role of interferon (IFN) …

Severe acute respiratory syndrome

…, SM Poutanen, MR Loutfy, MP Muller… - Clinical infectious …, 2004 - academic.oup.com
The first cases of severe acute respiratory syndrome (SARS) occurred in China in November
2002. The agent causing this illness has been identified as a novel coronavirus, SARS-…

Appendiceal abscess: immediate operation or percutaneous drainage?

CVR Brown, M Abrishami, M Muller… - The American …, 2003 - journals.sagepub.com
Conflicting evidence exists regarding the optimal treatment for abscess complicating acute
appendicitis. The objective of this study is to compare immediate appendectomy (IMM APP) …

Can routine laboratory tests discriminate between severe acute respiratory syndrome and other causes of community-acquired pneumonia?

MP Muller, G Tomlinson, TJ Marrie… - Clinical infectious …, 2005 - academic.oup.com
Background . The clinical presentation of severe acute respiratory syndrome (SARS) resembles
that of other etiologies of community-acquired pneumonia, making diagnosis difficult. …

Successful management of severe group A streptococcal soft tissue infections using an aggressive medical regimen including intravenous polyspecific …

A Norrby-Teglund, MP Muller, A McGeer… - … journal of infectious …, 2005 - Taylor & Francis
Intravenous polyspecific immunoglobulin G (IVIG) has been reported to be efficacious as
adjunctive therapy in patients with toxic shock syndrome caused by group A streptococci (GAS). …

[HTML][HTML] The impact of infection on population health: results of the Ontario burden of infectious diseases study

…, SE Majowicz, T Mazzulli, AJ McGeer, MP Muller… - 2012 - journals.plos.org
Background Evidence-based priority setting is increasingly important for rationally distributing
scarce health resources and for guiding future health research. We sought to quantify the …