• The instrument successfully differentiates between highand low-quality guideline content. 7•
The new user’s manual is well received by users. 7• Users provided considerable …

Background Guidelines continue to be underutilized, and a variety of strategies to improve
their use have been suboptimal. Modifying guideline features represents an alternative, but …

Purpose To address whether all medically fit patients with curatively resected stage II colon
cancer should be offered adjuvant chemotherapy as part of routine clinical practice, to …

AGREE II is a widely used standard for assessing the methodological quality of practice
guidelines. This article describes the development of the AGREE Reporting Checklist, which …

Background: We established a program of research to improve the development, reporting
and evaluation of practice guidelines. We assessed the construct validity of the items and user…

Background: We undertook research to improve the AGREE instrument, a tool used to evaluate
guidelines. We tested a new seven-point scale, evaluated the usefulness of the original …

Purpose: The objective of this study was to synthesize what is known about the relationship
between delay in radiotherapy (RT) and the outcomes of RT. Methods: A systematic review …

Radioactive iodine remnant ablation destroys residual thyroid tissue after surgical resection
of papillary or follicular thyroid cancer. We systematically reviewed 1543 English references …

Purpose To develop a systematic review that would address the following question: Should
patients with stage II colon cancer receive adjuvant therapy? Methods A systematic review …

… Brouwers, Gail Darling, Peter M. Ellis, Laurie E. Gaspar, Harvey I. … Brouwers, Gail
Darling, Peter M. Ellis, Harvey I. Pass, David R. … Brouwers …