[HTML][HTML] Smooth muscle phosphatase is regulated in vivo by exclusion of phosphorylation of threonine 696 of MYPT1 by phosphorylation of Serine 695 in response to …

…, JA MacDonald, F Erdodi, C Ma, MA Borman… - Journal of Biological …, 2004 - ASBMB
Regulation of smooth muscle myosin phosphatase (SMPP-1M) is thought to be a primary
mechanism for explaining Ca 2+ sensitization/desensitization in smooth muscle. Ca 2+ …

Identification of the endogenous smooth muscle myosin phosphatase-associated kinase

JA MacDonald, MA Borman… - Proceedings of the …, 2001 - National Acad Sciences
Ca 2+ sensitization of smooth muscle contraction involves inhibition of myosin light chain
phosphatase (SMPP-1M) and enhanced myosin light chain phosphorylation. Inhibition of SMPP…

[HTML][HTML] Dual Ser and Thr phosphorylation of CPI-17, an inhibitor of myosin phosphatase, by MYPT-associated kinase

JA MacDonald, M Eto, MA Borman, DL Brautigan… - FEBS letters, 2001 - Elsevier
Phosphorylation of CPI-17 and PHI-1 by the MYPT1-associated kinase (M110 kinase) was
investigated. M110 kinase is a recently identified serine/threonine kinase with a catalytic …

Integrin-linked kinase is responsible for Ca2+-independent myosin diphosphorylation and contraction of vascular smooth muscle

DP Wilson, C Sutherland, MA Borman… - Biochemical …, 2005 - portlandpress.com
Smooth muscle contraction is activated by phosphorylation at Ser-19 of LC 20 (the 20 kDa
light chains of myosin II) by Ca 2+ /calmodulin-dependent MLCK (myosin light-chain kinase). …

[HTML][HTML] Smooth muscle myosin phosphatase-associated kinase induces Ca2+ sensitization via myosin phosphatase inhibition

MA Borman, JA MacDonald, A Murányi… - Journal of Biological …, 2002 - ASBMB
Smooth muscle calcium sensitization reflects an inhibition of myosin light chain phosphatase
(SMPP-1m) activity; however, the underlying mechanisms are not well understood. SMPP-…

[HTML][HTML] Validation of coding algorithms for the identification of patients hospitalized for alcoholic hepatitis using administrative data

JXQ Pang, E Ross, MA Borman, S Zimmer… - BMC …, 2015 - Springer
Background Epidemiologic studies of alcoholic hepatitis (AH) have been hindered by the
lack of a validated International Classification of Disease (ICD) coding algorithm for use with …

The role of the calponin homology domain of smoothelin-like 1 (SMTNL1) in myosin phosphatase inhibition and smooth muscle contraction

MA Borman, TA Freed, TAJ Haystead… - Molecular and cellular …, 2009 - Springer
In this study, we provide further insight into the contribution of the smoothelin-like 1 (SMTNL1)
calponin homology (CH)-domain on myosin light chain phosphatase (SMPP-1M) activity …

[HTML][HTML] Modulation of smooth muscle contractility by CHASM, a novel member of the smoothelin family of proteins

MA Borman, JA MacDonald, TAJ Haystead - FEBS letters, 2004 - Elsevier
Cyclic nucleotides acting through their associated protein kinases, the cGMP- and cAMP-dependent
protein kinases, can relax smooth muscles without a change in free intracellular …

Real‐world clinical and virological outcomes in a retrospective multiethnic cohort study of 341 untreated and tenofovir disoproxil fumarate‐treated chronic hepatitis B …

…, AII Aspinall, LM Stinton, MA Borman… - Alimentary …, 2020 - Wiley Online Library
Background There are limited long‐term data on outcomes of chronic hepatitis B (CHB) in
untreated and tenofovir disoproxil fumarate (TDF)‐treated women during pregnancy. Aims To …

[HTML][HTML] Solution structure of the calponin homology (CH) domain from the smoothelin-like 1 protein: a unique apocalmodulin-binding mode and the possible role of …

H Ishida, MA Borman, J Ostrander, HJ Vogel… - Journal of biological …, 2008 - ASBMB
The SMTNL1 protein contains a single type-2 calponin homology (CH) domain at its C
terminus that shares sequence identity with the smoothelin family of smooth muscle-specific …