Inflammation is involved in the pathophysiology of Alzheimer’s disease (AD), with multiple
inflammatory processes implicated in its risk and progression. This review included original …

Type 2 diabetes mellitus (T2DM) is an important risk factor for dementia. The possibility to
mitigate this risk by controlling T2DM is compelling; however, different glucose-lowering drugs …

Background Mixed evidence supports blood-brain barrier (BBB) dysfunction in Lewy body
spectrum diseases. Methods We compare biofluid markers in people with idiopathic …

Introduction Few studies have examined memory decline among patients with type 2 diabetes
using different oral hypoglycemic drugs. Methods Participants with normal cognition (NC) …

Background The antihypertensive angiotensin receptor blockers (ARBs) and angiotensin-converting
enzyme inhibitors (ACE-Is) have similar indications and mechanisms of action, but …

Background Studies suggest a role of the innate immune system, including the activity of
neutrophils, in neurodegeneration related to Alzheimer’s disease (AD), but prospective …

Some studies suggest that angiotensin II type 1 receptor blockers (ARBs) may protect against
memory decline more than angiotensin-converting enzyme inhibitors (ACE-Is), but few …

Background and Purpose: Many patients with ischemic stroke present with multiple comorbidities
that threaten survival and recovery. This study sought to determine the risks of adverse …

Background The incidence of ischemic stroke has increased among adults aged 18 to 64
years, yet little is known about relationships between specific risk factors and outcomes. This …

Background: The endosomal-lysosomal and autophagy (ELA) pathway may be implicated
in the progression of Alzheimer’s disease (AD); however, findings thus far have been …