Background Cerebral sinovenous thrombosis in children is a serious disorder, and information
is needed about its prevention and treatment. Methods The Canadian Pediatric Ischemic …

Global developmental delay and intellectual disability are relatively common pediatric
conditions. This report describes the recommended clinical genetics diagnostic approach. The …

The objective of this study was to characterize participation in leisure activities in children with
cerebral palsy (CP) and identify determinants of greater involvement. Ninety‐five children …

Ion-channel gene defects are associated with a range of paroxysmal disorders, including
several monogenic epilepsy syndromes. Two autosomal dominant disorders present in the first …

OBJECTIVES. Our goal for this study was to prospectively test whether parent-completed
questionnaires can be effectively used in the setting of a busy ambulatory pediatric clinic to …

An estimated 5 to 10% of the pediatric population has a developmental disability. The current
strategy to identify these children is through developmental surveillance, a continuous …

Objectives: To determine the prevalence of persistent developmental impairments in
children with congenital heart defects and to identify factors that enhance risk for an adverse …

Little is known about the genetics of nonsyndromic intellectual disability (NSID). We
hypothesized that de novo mutations (DNMs) in synaptic genes explain an important fraction of …

This clinical report describes the clinical genetic evaluation of the child with developmental
delays or mental retardation. The purpose of this report is to describe the optimal clinical …

Background: Neurodevelopmental disabilities in children with congenital heart defects (CHDs)
have been primarily attributed to intraoperative events without consideration of …