Oxidized phosphatidylcholines trigger TRPA1 and ryanodine receptor–dependent airway smooth muscle contraction
…, A Sikarwar, D Mangat, M Ragheb… - American Journal of …, 2023 - atsjournals.org
Asthma pathobiology includes oxidative stress that modifies cell membranes and extracellular
phospholipids. Oxidized phosphatidylcholines (OxPCs) in lung lavage from allergen-…
phospholipids. Oxidized phosphatidylcholines (OxPCs) in lung lavage from allergen-…
Allergen inhalation generates pro-inflammatory oxidised phosphatidylcholine associated with airway dysfunction
Oxidised phosphatidylcholines (OxPCs) are produced under conditions of elevated oxidative
stress and can contribute to human disease pathobiology. However, their role in allergic …
stress and can contribute to human disease pathobiology. However, their role in allergic …
Glucocorticoids for croup in children
Background Glucocorticoids are the mainstay for the treatment of croup. The existing
evidence demonstrates that glucocorticoids are effective in the treatment of croup in children. …
evidence demonstrates that glucocorticoids are effective in the treatment of croup in children. …
[HTML][HTML] Readiness of emergency departments for pediatric patients and pediatric mortality: a systematic review
…, AC Coyle, C Tam, M Skakum, M Ragheb… - … Open Access Journal, 2023 - cmajopen.ca
Background: Most children who need emergency care visit general emergency departments
and urgent care centres; the weighted pediatric readiness score (WPRS) is currently used to …
and urgent care centres; the weighted pediatric readiness score (WPRS) is currently used to …
MicroRNAs: Small molecules with significant functions, particularly in the context of viral hepatitis B and C infection
… miRNAs significantly participate in intercellular signaling, circulating miRNAs (exogenous
miRNAs… extracellular signaling, and are defined as miRNAs that are found inside cells that can …
miRNAs… extracellular signaling, and are defined as miRNAs that are found inside cells that can …
MicroRNA-372-3p predicts response of TACE patients treated with doxorubicin and enhances chemosensitivity in hepatocellular carcinoma
MH Soliman, MA Ragheb, EM Elzayat… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
… miRNA expression is a common characteristic in numerous cancers including HCC. Studies
have exhibited that many of the human miRNAs are … Several miRNAs may have possible …
have exhibited that many of the human miRNAs are … Several miRNAs may have possible …
Call to action: equity, diversity, and inclusion in emergency medicine resident physician selection
…, F Fovet, J Gallinger, J Mohadeb, M Ragheb… - Canadian Journal of …, 2023 - Springer
Objectives This call to action seeks to improve emergency care in Canada for equity-deserving
communities, enabled by equitable representation among emergency physicians …
communities, enabled by equitable representation among emergency physicians …
Oxidized phosphatidylcholine induces COX2 gene expression and cytokine secretion by human airway smooth muscle cells
CD Pascoe, M Ragheb, G Stelmack, A Jha… - … MARKERS OF LUNG …, 2017 - atsjournals.org
Mechanisms to maintain redox balance in the lungs are overwhelmed in severe asthma,
resulting in oxidative damage. The Rationale: phosphatidylcholine (PC)-rich lining of the lung is …
resulting in oxidative damage. The Rationale: phosphatidylcholine (PC)-rich lining of the lung is …
MicroRNA-520c-3p modulates doxorubicin-chemosensitivity in HepG2 Cells
MA Ragheb, MH Soliman, EM Elzayat… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
… In order to examine the miRNAs expression profiles in DOXtreated cells, we analyzed the
levels of 384 miRNAs with irregular expression in liver-associated diseases, including HCC, …
levels of 384 miRNAs with irregular expression in liver-associated diseases, including HCC, …
Caffeic acid modulates miR-636 expression in diabetic nephropathy rats
AM Salem, AS Ragheb, MGA Hegazy… - Indian Journal of Clinical …, 2019 - Springer
… This study was conducted due to the important miRNAs in complications of diabetes and …
We had a bioinformatics analysis to retrieve and choose a miRNA (miR-636) relevant to DKD …
We had a bioinformatics analysis to retrieve and choose a miRNA (miR-636) relevant to DKD …