Background Lenvatinib, an oral inhibitor of vascular endothelial growth factor receptors 1, 2,
and 3, fibroblast growth factor receptors 1 through 4, platelet-derived growth factor receptor α…

Purpose To address whether all medically fit patients with curatively resected stage II colon
cancer should be offered adjuvant chemotherapy as part of routine clinical practice, to …

Background Cancer patients receive numerous medications, including antineoplastic agents,
drugs for supportive care, and medications for comorbid illnesses. Therefore, they are at …

Purpose Cancer-related fatigue (CRF) is the most prevalent and distressing symptom among
cancer patients and survivors. However, research on its prevalence and related disability in …

ContextLarge clinical trials are the criterion standard for making treatment decisions, and
nonpublication of the results of such trials can lead to bias in the literature and contribute to …

Purpose To describe current referral practices of oncologists to specialized palliative care (SPC)
and define demographic characteristics, practice situations, and opinions associated …

Background The clinical utility of molecular profiling of tumor tissue to guide treatment of
patients with advanced solid tumors is unknown. Our objectives were to evaluate the frequency …

Background The treatment of cancer in patients with comorbidities can be challenging as
these individuals are underrepresented in clinical trials. We conducted a systematic review to …

Purpose: Communicating about the end of life with patients has been reported as one of the
most difficult and stressful part of the work of oncologists. Despite this fact, oncologists …

… Krzyzanowska, RB Cohen, and C. Chung have research support from AstraZeneca. RB …
Krzyzanowska have research support from Exelixis. RB Cohen has research support from …