Background Data regarding high-sensitivity troponin concentrations in patients presenting
to the emergency department with symptoms suggestive of myocardial infarction may be …

Importance Rapid and accurate diagnosis of acute myocardial infarction (AMI) currently
constitutes an unmet need. Objective To test a 1-hour diagnostic algorithm to diagnose AMI …

Importance High-sensitivity cardiac troponin I testing is widely used to evaluate patients with
suspected acute coronary syndrome. A cardiac troponin concentration of less than 5 ng/L …

Troponin is a widely used biomarker in patients with cardiac disease. The use of troponin is
well established in patients with suspected acute myocardial infarction (AMI), but troponin …

Increased afterload results in ‘pathological’ cardiac hypertrophy, the most important risk
factor for the development of heart failure. Current in vitro models fall short in deciphering the …

Background : The safety of the European Society of Cardiology (ESC) 0/1-h algorithm for
rapid rule-out and rule-in of non–ST-segment elevation myocardial infarction (NSTEMI) using …

Background The Society of Cardiovascular Angiography and Interventions (SCAI) have
recently proposed a new classification of cardiogenic shock (CS) dividing patients into five …

Background: The 2020 European Society of Cardiology (ESC) guidelines recommend using
the 0/1-hour and 0/2-hour algorithms over the 0/3-hour algorithm as the first and second …

Aims The differentiation of type 1 and type 2 myocardial infarction (T1MI, T2MI) is important,
but challenging in the emergency department. We aimed to investigate the clinical …

Aims We aimed to evaluate the impact of age on the performance of the European Society
of Cardiology (ESC) 0/1h-algorithms and to derive and externally validate alternative cut-offs …