User profiles for Patrick E. Steadman
Patrick SteadmanFaculty of Medicine, University of Toronto Verified email at mail.utoronto.ca Cited by 1589 |
[PDF][PDF] Disruption of oligodendrogenesis impairs memory consolidation in adult mice
… Steadman et al. find that blocking this form of adaptive myelination prevents learning-induced …
(D and E) Mrf deletion decreased the density of tagged oligodendrocyte lineage cells (D) …
(D and E) Mrf deletion decreased the density of tagged oligodendrocyte lineage cells (D) …
[PDF][PDF] Chemogenetic interrogation of a brain-wide fear memory network in mice
Behavior depends on coordinated activity across multiple brain regions. Within such networks,
highly connected hub regions are assumed to disproportionately influence behavioral …
highly connected hub regions are assumed to disproportionately influence behavioral …
Genetic effects on cerebellar structure across mouse models of autism using a magnetic resonance imaging atlas
Magnetic resonance imaging ( MRI ) of autism populations is confounded by the inherent
heterogeneity in the individuals' genetics and environment, two factors difficult to control for. …
heterogeneity in the individuals' genetics and environment, two factors difficult to control for. …
[PDF][PDF] Mesenchymal precursor cells in adult nerves contribute to mammalian tissue repair and regeneration
Peripheral innervation plays an important role in regulating tissue repair and regeneration.
Here we provide evidence that injured peripheral nerves provide a reservoir of mesenchymal …
Here we provide evidence that injured peripheral nerves provide a reservoir of mesenchymal …
Memory formation in the absence of experience
Memory is coded by patterns of neural activity in distinct circuits. Therefore, it should be
possible to reverse engineer a memory by artificially creating these patterns of activity in the …
possible to reverse engineer a memory by artificially creating these patterns of activity in the …
A 3D adult zebrafish brain atlas (AZBA) for the digital age
Zebrafish have made significant contributions to our understanding of the vertebrate brain
and the neural basis of behavior, earning a place as one of the most widely used model …
and the neural basis of behavior, earning a place as one of the most widely used model …
MRI-detectable changes in mouse brain structure induced by voluntary exercise
Physical exercise, besides improving cognitive and mental health, is known to cause structural
changes in the brain. Understanding the structural changes that occur with exercise as …
changes in the brain. Understanding the structural changes that occur with exercise as …
Sex differences in neurology: a scoping review
Objective Historically, neurology research has demonstrated a sex bias with mainly male
subjects included in clinical trials as well as lack of reporting of data by sex. In recent years, …
subjects included in clinical trials as well as lack of reporting of data by sex. In recent years, …
Characteristics and outcomes of Canadian MD/PhD program graduates: a cross-sectional survey
Background: Combined MD/PhD programs provide a structured path for physician-scientist
training, but assessment of their success within Canada is limited by a lack of quantitative …
training, but assessment of their success within Canada is limited by a lack of quantitative …
Training the next generation of Canadian Clinician-Scientists: charting a path to success
Clinician-scientists are physicians with training in both clinical medicine and research that
enables them to occupy a unique niche as specialists in basic and translational biomedical …
enables them to occupy a unique niche as specialists in basic and translational biomedical …