User profiles for Paul Yong
Paul YongUniversity of British Columbia Verified email at cw.bc.ca Cited by 5704 |
[HTML][HTML] Cancer-associated mutations in endometriosis without cancer
Background Endometriosis, defined as the presence of ectopic endometrial stroma and
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic pain …
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic pain …
Assessing research gaps and unmet needs in endometriosis
Endometriosis, a systemic disease that is often painful and chronic, affects ∼10% of
reproductive-age women. The disease can have a negative impact on a patient’s physical and …
reproductive-age women. The disease can have a negative impact on a patient’s physical and …
[HTML][HTML] Intricate connections between the microbiota and endometriosis
I Jiang, PJ Yong, C Allaire, MA Bedaiwy - International Journal of …, 2021 - mdpi.com
Imbalances in gut and reproductive tract microbiota composition, known as dysbiosis,
disrupt normal immune function, leading to the elevation of proinflammatory cytokines, …
disrupt normal immune function, leading to the elevation of proinflammatory cytokines, …
Multifactorial contributors to the severity of chronic pelvic pain in women
Background Chronic pelvic pain affects ∼15% of women, and is associated with significant
societal cost and impact on women’s health. Identifying factors involved in chronic pelvic …
societal cost and impact on women’s health. Identifying factors involved in chronic pelvic …
[HTML][HTML] New developments in the medical treatment of endometriosis
MA Bedaiwy, S Alfaraj, P Yong, R Casper - Fertility and sterility, 2017 - Elsevier
Endometriosis affects 1 in 10 women of reproductive-age. The current treatments are
surgical and hormonal but have limitations, including the risk of recurrence, side effects, …
surgical and hormonal but have limitations, including the risk of recurrence, side effects, …
Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden
Endometriosis is a significant risk factor for clear cell and endometrioid ovarian cancers and
is often found contiguous with these cancers. Using whole‐genome shotgun sequencing of …
is often found contiguous with these cancers. Using whole‐genome shotgun sequencing of …
The evolution of gene duplicates
Gene and genome duplications have given rise to enormous variability among species in the
number of genes within their genomes. Gene copies have in turn played important roles in …
number of genes within their genomes. Gene copies have in turn played important roles in …
Impact of a multidisciplinary vulvodynia program on sexual functioning and dyspareunia
Introduction For many years, multidisciplinary approaches, which integrate psychological,
physical, and medical treatments, have been shown to be effective for the treatment of chronic …
physical, and medical treatments, have been shown to be effective for the treatment of chronic …
Chronic pelvic pain in an interdisciplinary setting: 1-year prospective cohort
Background Chronic pelvic pain affects ∼15% of women, and presents a challenging problem
for gynecologists due to its complex etiology involving multiple comorbidities. Thus, an …
for gynecologists due to its complex etiology involving multiple comorbidities. Thus, an …
Decidual NK cells alter in vitro first trimester extravillous cytotrophoblast migration: a role for IFN-γ
Y Hu, JP Dutz, CD MacCalman, P Yong… - The Journal of …, 2006 - journals.aai.org
Abnormal placentation results in either inadequate (consequences: recurrent miscarriage,
intrauterine growth restriction, and preeclampsia) or overzealous (consequences: placenta …
intrauterine growth restriction, and preeclampsia) or overzealous (consequences: placenta …