User profiles for Paul Yong

Paul Yong

University of British Columbia
Verified email at cw.bc.ca
Cited by 5704

[HTML][HTML] Cancer-associated mutations in endometriosis without cancer

…, L Diaz, TL Wang, B Vogelstein, PJ Yong… - … England Journal of …, 2017 - Mass Medical Soc
Background Endometriosis, defined as the presence of ectopic endometrial stroma and
epithelium, affects approximately 10% of reproductive-age women and can cause pelvic pain …

Assessing research gaps and unmet needs in endometriosis

…, RN Taylor, K Wallace, Z Williams, PJ Yong… - American journal of …, 2019 - Elsevier
Endometriosis, a systemic disease that is often painful and chronic, affects ∼10% of
reproductive-age women. The disease can have a negative impact on a patient’s physical and …

[HTML][HTML] Intricate connections between the microbiota and endometriosis

I Jiang, PJ Yong, C Allaire, MA Bedaiwy - International Journal of …, 2021 - mdpi.com
Imbalances in gut and reproductive tract microbiota composition, known as dysbiosis,
disrupt normal immune function, leading to the elevation of proinflammatory cytokines, …

Multifactorial contributors to the severity of chronic pelvic pain in women

…, MS Abdellah, F Wong, S Lisonkova, PJ Yong - American journal of …, 2016 - Elsevier
Background Chronic pelvic pain affects ∼15% of women, and is associated with significant
societal cost and impact on women’s health. Identifying factors involved in chronic pelvic …

[HTML][HTML] New developments in the medical treatment of endometriosis

MA Bedaiwy, S Alfaraj, P Yong, R Casper - Fertility and sterility, 2017 - Elsevier
Endometriosis affects 1 in 10 women of reproductive-age. The current treatments are
surgical and hormonal but have limitations, including the risk of recurrence, side effects, …

Multifocal endometriotic lesions associated with cancer are clonal and carry a high mutation burden

…, AN Karnezis, MA Marra, PJ Yong… - The Journal of …, 2015 - Wiley Online Library
Endometriosis is a significant risk factor for clear cell and endometrioid ovarian cancers and
is often found contiguous with these cancers. Using whole‐genome shotgun sequencing of …

The evolution of gene duplicates

SP Otto, P Yong - Advances in genetics, 2002 - Elsevier
Gene and genome duplications have given rise to enormous variability among species in the
number of genes within their genomes. Gene copies have in turn played important roles in …

Impact of a multidisciplinary vulvodynia program on sexual functioning and dyspareunia

LA Brotto, P Yong, KB Smith… - The journal of sexual …, 2015 - academic.oup.com
Introduction For many years, multidisciplinary approaches, which integrate psychological,
physical, and medical treatments, have been shown to be effective for the treatment of chronic …

Chronic pelvic pain in an interdisciplinary setting: 1-year prospective cohort

…, MA Bedaiwy, AY Albert, S Lisonkova, PJ Yong - American journal of …, 2018 - Elsevier
Background Chronic pelvic pain affects ∼15% of women, and presents a challenging problem
for gynecologists due to its complex etiology involving multiple comorbidities. Thus, an …

Decidual NK cells alter in vitro first trimester extravillous cytotrophoblast migration: a role for IFN-γ

Y Hu, JP Dutz, CD MacCalman, P Yong… - The Journal of …, 2006 - journals.aai.org
Abnormal placentation results in either inadequate (consequences: recurrent miscarriage,
intrauterine growth restriction, and preeclampsia) or overzealous (consequences: placenta …