Background Atrial fibrillation is a common post‐operative complication of cardiac surgery and
is associated with an increased risk of post‐operative stroke, increased length of intensive …

Background Cardiopulmonary bypass initiates a systemic inflammatory response syndrome
that is associated with postoperative morbidity and mortality. Steroids suppress inflammatory …

Background Antithrombotic therapy in valvular disease is important to mitigate thromboembolism,
but the hemorrhagic risk imposed must be considered. Methods The methods of this …

Background There is substantial variability in the perioperative administration of aspirin in
patients undergoing noncardiac surgery, both among patients who are already on an aspirin …

Background The relative benefits and risks of performing coronary-artery bypass grafting (CABG)
with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary …

Background Surgical occlusion of the left atrial appendage has been hypothesized to
prevent ischemic stroke in patients with atrial fibrillation, but this has not been proved. The …

Background The effect of a restrictive versus liberal red-cell transfusion strategy on clinical
outcomes in patients undergoing cardiac surgery remains unclear. Methods In this multicenter…

The Canadian Cardiovascular Society (CCS) atrial fibrillation (AF) guidelines program was
developed to aid clinicians in the management of these complex patients, as well as to …

Importance Little is known about the relationship between perioperative high-sensitivity
troponin T (hsTnT) measurements and 30-day mortality and myocardial injury after noncardiac …

Background Previously, we reported that there was no significant difference at 30 days in
the rate of a primary composite outcome of death, myocardial infarction, stroke, or new renal …