Ursodeoxycholic acid, a dihydroxyl bile acid normally present in human beings in minimal
amounts, becomes incorporated into the bile salt pool when taken orally. In cholestasis, bile …

Breath tests are a simple and safe alternative to more invasive investigation strategies for
many gastroenterological conditions. Both the hydrogen breath tests and the new 13 C stable …

Background & Aims Probiotic formulations of single species of bacteria have not been effective
in preventing the recurrence of Crohn’s disease after surgery. We investigated the ability …

OBJECTIVES: Screening tools to determine which outpatients with cirrhosis are at highest
risk forunplannedhospitalization are lacking. Frailty is a novel prognostic factor but …

Cirrhosis patients have reduced peak aerobic power (peak VO 2 ) that is associated with
reduced survival. Supervised exercise training increases exercise tolerance. The effect of home-…

The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila
melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate …

Background and Aims The Liver Frailty Index (LFI) is a well‐studied tool that evaluates frailty
in patients with cirrhosis. Consisting of grip strength, chair stands, and balance testing, the …

OBJECTIVE: Although there is general agreement that conception should be avoided when
Crohn's disease is active, many questions remain unanswered for the woman with Crohn's …

Background Depression is associated with substantial morbidity and mortality in cirrhosis,
but is underdiagnosed and undertreated. Aims Using the Mini International Neuropsychiatric …

Abstract Treatment of patients with primary biliary cirrhosis (PBC) using ursodeoxycholic
acid (UDCA) leads to a reduction in serum bilirubin. The first objective of this study was to …