Surveillance of drug-resistant bacteria is essential for healthcare providers to deliver
effective empirical antibiotic therapy. However, traditional molecular epidemiology does not …

Nunavik, Québec suffers from epidemic tuberculosis (TB), with an incidence 50-fold higher
than the Canadian average. Molecular studies in this region have documented limited …

Background Antimicrobial-resistant Neisseria gonorrhoeae is a major threat to public health.
No studies to date have examined the genomic epidemiology of gonorrhoea in the Western …

Background. Between November 2011 and November 2012, a Canadian village of 933
persons had 50 culture-positive cases of tuberculosis, with 49 sharing the same genotype. …

Tuberculosis disproportionately affects the Canadian Inuit. To address this, it is imperative
we understand transmission dynamics in this population. We investigate whether ‘deep’ …

Whole-genome sequencing has taken a leading role in epidemiologic studies of tuberculosis,
but thus far, its real-time clinical utility has been low, in part because of the requirement for …

• The overall incidence rate of active tuberculosis (TB) disease in Canada is low and has
remained unchanged in the last 10 years at around 4.6-5.1 individuals per 100,000 population, …

Background: Tuberculosis predominantly affects socioeconomically disadvantaged
communities. The extent to which specific dietary and lifestyle factors contribute to tuberculosis …

The availability of whole-genome sequencing (WGS) as a tool for the diagnosis and clinical
management of tuberculosis (TB) offers considerable promise in the fight against this …

Background Vancomycin-resistant Enterococcus faecium (VREfm) represent a major source
of nosocomial infection worldwide. In Australia, there has been a recent concerning …