Background: Medication-related visits to the emergency department are an important but
poorly understood phenomenon. We sought to evaluate the frequency, severity and …

STUDY OBJECTIVE: Adverse drug events represent the most common cause of preventable
nonsurgical adverse events in medicine but may remain undetected. Our objective is to …

Aim We conducted a responsibility analysis to determine whether drivers injured in motor
vehicle collisions who test positive for Δ‐9‐tetrahydrocannabinol (THC) or other drugs are …

Study Objectives: We sought to evaluate the relationship between osmolal gap and serum
ethanol level and derive a formula that can be used clinically to calculate the expected …

STUDY OBJECTIVE: To compare outcomes after acute acetaminophen poisoning in 2 large
cohorts of patients treated with either the 20-hour intravenous or 72-hour oral acetylcysteine …

Introduction Increased use of crystal methamphetamine (“crystal meth”) has been observed
across North America and international jurisdictions, including a notable increase in the …

STUDY OBJECTIVE: We investigate adverse drug events associated with antidotes ethanol
and fomepizole in methanol or ethylene glycol poisonings. An “adverse drug event” is harm …

Objectives Determine the prevalence of drug use in injured drivers and identify associated
demographic factors and crash characteristics. Design Prospective cross-sectional study. …

Objective To assess the association between long term prescription opioid treatment
medically dispensed for non-cancer pain and the initiation of injection drug use (IDU) among …

Background Anaphylactoid reactions to intravenous (IV) N-acetylcysteine (NAC) are well-recognized
adverse events during treatment for acetaminophen (APAP) poisoning. Uncertainty …