Comprehensive profiling of plasma fatty acid concentrations in young healthy Canadian adults

SA Abdelmagid, SE Clarke, DE Nielsen, A Badawi… - PloS one, 2015 - journals.plos.org
Circulating fatty acids (FA) are associated with a multitude of chronic diseases. However, a
major gap in establishing such relationships is the lack of accepted fatty acid reference …

CAT‐1‐mediated arginine uptake and regulation of nitric oxide synthases for the survival of human breast cancer cell lines

SA Abdelmagid, JA Rickard… - Journal of cellular …, 2011 - Wiley Online Library
Growth of the human MCF‐7 breast cancer cell line is highly dependent on L‐arginine. We
have reported that L‐arginine, released from extracellular substrates by prolactin (PRL)‐ and …

Plasma levels of 14: 0, 16: 0, 16: 1n-7, and 20: 3n-6 are positively associated, but 18: 0 and 18: 2n-6 are inversely associated with markers of inflammation in young …

…, K Roke, A Badawi, DE Nielsen, SA Abdelmagid… - Lipids, 2014 - Springer
Inflammation is a recognized risk factor for the development of chronic diseases, such as
type 2 diabetes and atherosclerosis. Evidence suggests that individual fatty acids (FA) may …

[HTML][HTML] Marine fish oil is more potent than plant-based n-3 polyunsaturated fatty acids in the prevention of mammary tumors

J Liu, SA Abdelmagid, CJ Pinelli, JM Monk… - The Journal of …, 2018 - Elsevier
Marine-derived n-3 polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), have been shown to inhibit mammary carcinogenesis. …

Ethnicity, sex, FADS genetic variation, and hormonal contraceptive use influence delta-5-and delta-6-desaturase indices and plasma docosahexaenoic acid …

SA Abdelmagid, SE Clarke, K Roke, DE Nielsen… - Nutrition & …, 2015 - Springer
Background There is great interest in the relationship between polyunsaturated fatty acids and
health. Yet, the combinatory effect of factors such as sex, ethnicity, genetic polymorphisms …

Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells

SA Abdelmagid, CKL Too - Endocrinology, 2008 - academic.oup.com
Carboxypeptidase-D (CPD) and carboxypeptidase-M (CPM) release C-terminal arginine (Arg)
from polypeptides, and both are present in the plasma membrane. Cell-surface CPD …

[HTML][HTML] The delta 6 desaturase knock out mouse reveals that immunomodulatory effects of essential n-6 and n-3 polyunsaturated fatty acids are both independent of …

…, DH Tsang, LM Hillyer, SA Abdelmagid… - The Journal of …, 2016 - Elsevier
Typically fatty acids (FA) exert differential immunomodulatory effects with n-3 [α-linolenic
acid (ALA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] and n-6 [linoleic …

Mammary tumour development is dose-dependently inhibited by n-3 polyunsaturated fatty acids in the MMTV-neu (ndl)-YD5 transgenic mouse model

MA Leslie, SA Abdelmagid, K Perez, WJ Muller… - Lipids in health and …, 2014 - Springer
Background Breast cancer is attributable to modifiable risk factors including the intake of
dietary n-3 polyunsaturated fatty acids (PUFA). A key piece of evidence, yet to be addressed, …

Role of n-3 polyunsaturated fatty acids and exercise in breast cancer prevention: identifying common targets

SA Abdelmagid, JL MacKinnon… - Nutrition and …, 2016 - journals.sagepub.com
Diet and exercise are recognized as important lifestyle factors that significantly influence
breast cancer risk. In particular, dietary n-3 polyunsaturated fatty acids (PUFAs) have been …

Plasma concentration of cis 9trans 11 CLA in males and females is influenced by SCD1 genetic variations and hormonal contraceptives: a cross-sectional study

SA Abdelmagid, SE Clarke, J Wong, K Roke… - Nutrition & …, 2013 - Springer
Plasma concentration of cis 9trans 11 CLA in males and females is influenced by SCD1 genetic
variations and hormonal contraceptives: a cross-sectional study | Nutrition & Metabolism …